Membrane Humidifier Architecture for Low-Pressure Nasal Insufflation

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Solution Overview

Problem

Conventional high flow therapy systems require high pressure sources due to increased resistance from membrane humidifiers and large bore cannulas, limiting their use in environments without access to pressurized gas, and non-membrane humidifiers fail to effectively flush CO2 and produce lower quality vapor.

Innovation Solution

A low pressure system architecture using a blower, vapor transfer unit with a membrane, and a nasal cannula with separate flow paths and large bore delivery tubes, integrated gas and liquid paths within a single tube, and a flexible film breech lock to maintain system integrity and reduce energy consumption.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If a membrane humidifier is used to humidify breathing gas, then vapor quality is improved, but pressure requirements increase due to higher flow resistance

Engineering Contradiction:
Improvevapor qualityVSAvoidpressure requirements
Core Design Contradiction:
Manufacturing precisionVSStress or pressure

Solution Approach 1:

The liquid delivery line is nested within the gas delivery tube, allowing both fluid paths to share the same external housing and routing infrastructure. This reduces the number of separate components and connections, thereby reducing overall system resistance while maintaining effective humidification through the membrane.

Inventive Principle:
Principle #7Nested doll (Nesting)

2Productivity

If a small bore nasal cannula is used to increase gas velocity, then CO2 flushing is improved, but pressure requirements increase

Engineering Contradiction:
ImproveCO2 flushing effectivenessVSAvoidpressure requirements
Core Design Contradiction:
ProductivityVSStress or pressure

Solution Approach 1:

The nasal cannula is designed with separate flow paths for gas delivery and liquid delivery, allowing each function to be optimized independently. The gas path uses a small bore design for high velocity and CO2 flushing, while the liquid path has its own dedicated route to the membrane humidifier, preventing the liquid delivery requirements from increasing the pressure needed for gas delivery.

Inventive Principle:
Principle #1Segmentation

3Stress or pressure

If a non-membrane humidifier is used to reduce pressure requirements, then system pressure is reduced, but CO2 flushing is insufficient and vapor quality is lower

Engineering Contradiction:
Improvepressure requirementsVSAvoidCO2 flushing effectiveness
Core Design Contradiction:
Stress or pressureVSProductivity

Solution Approach 1:

A membrane humidifier uses a porous or semi-permeable membrane that allows water vapor to pass through while maintaining a structured flow path. This membrane design enables effective CO2 flushing through controlled diffusion and convection, while also producing high-quality vapor through the membrane's vapor transfer properties, thus resolving the trade-off between pressure requirements and CO2 flushing effectiveness.

Inventive Principle:
Principle #31Porous materials

4Stress or pressure

If separate gas and liquid paths are used in the delivery tube, then flow resistance is reduced, but system complexity increases

Engineering Contradiction:
Improveflow resistanceVSAvoidsystem complexity
Core Design Contradiction:
Stress or pressureVSDevice complexity

Solution Approach 1:

The liquid delivery line is nested within the gas delivery tube, allowing both fluid paths to share the same external housing and routing infrastructure. This reduces the number of separate components and connections, thereby reducing overall system resistance while maintaining effective humidification through the membrane.

Inventive Principle:
Principle #7Nested doll (Nesting)

Solution Approach 2:

The gas and liquid delivery systems are merged into a single integrated tube assembly, where the liquid line is positioned within the gas line. This consolidation reduces the number of separate connections and interfaces required, simplifying the overall system architecture while maintaining separate flow paths to minimize resistance.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables operation with ambient pressure sources, reduces flow resistance, and maintains effective CO2 flushing and vapor quality, allowing use in various environments without pressurized gas availability.

Implementation Method 1

The membrane permits transfer of vapor into the gas passage from liquid in the liquid passage

Methodology Applied
Scientific EffectVapor transfer: Evaporation

Implementation Method 2

The base unit includes a blower. The blower delivers breathing gas to the gas passage of the vapor transfer unit

Methodology Applied
Scientific EffectForced convection: Forced Convection

Implementation Method 3

when liquid is in the liquid container, the liquid exerts pressure against the film, which in turn exerts pressure against the breech lock, causing friction

Methodology Applied
Scientific EffectFluid pressure: Pressure Increase

Implementation Method 4

the delivery tube insulates the liquid delivery line from ambient air

Methodology Applied
Scientific EffectThermal insulation: Thermal Insulation

Implementation Method 5

The liquid delivery line may carry heated liquid, so insulating the line can reduce the energy required to maintain the temperature of the line

Methodology Applied
Scientific EffectHeat exchange: Heat Exchanger

Data Source

PatentUS12599742B2Systems and methods for high velocity nasal insufflation
Publication Date: 2026.04.14 VAPOTHERM INC
  • US12599742B2 patent drawing
  • US12599742B2 patent drawing
  • US12599742B2 patent drawing

AI summary

Systems, methods, and devices for humidifying a breathing gas are presented. The system includes a base unit, a vapor transfer unit, a nasal cannula, and a liquid container. The base unit includes a blower. The vapor transfer unit is external to the base unit and includes a gas passage, a liquid passage, a gas outlet, and a membrane separating the gas passage and the liquid passage. The membrane permits transfer of vapor into the gas passage from liquid in the liquid passage. The nasal cannula is coupled to the gas outlet. The liquid container is configured to reversibly mate with the base unit.