Closed-Loop Memory Intervention Control via EEG Replay Detection

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Solution Overview

Problem

Current memory enhancement techniques lack the ability to selectively target specific memories for enhancement during sleep and cannot automatically control interventions based on real-time brain state analysis, leading to inefficient and ineffective memory consolidation.

Innovation Solution

A closed-loop intervention control system that uses a cognitive model-based predictive controller to simulate memory changes, predict behavioral performance, and control memory interventions during sleep by analyzing EEG data in real-time, allowing for targeted and efficient memory consolidation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If general memory enhancement interventions are applied during sleep, then overall memory consolidation is improved, but specific targeted enhancement of particular memories cannot be achieved

Engineering Contradiction:
Improvememory consolidation effectivenessVSAvoidselective memory targeting capability
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The system employs a closed-loop control architecture where EEG signals are continuously monitored during sleep, decoded to identify replay events, and used to provide feedback for triggering targeted interventions. This feedback mechanism enables the system to selectively enhance specific memories by detecting when they are being replayed and applying interventions at those precise moments, rather than applying general enhancements to all memories.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent introduces an intermediary layer consisting of EEG decoding algorithms and a cognitive model-based predictive controller that mediates between raw brain signals and intervention delivery. This intermediary system translates neural activity patterns into actionable information about which memories are being replayed, enabling selective targeting without requiring direct observation or control of the memories themselves.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If continuous memory interventions are applied during sleep, then memory retention is improved, but interference with other memory consolidation processes occurs

Engineering Contradiction:
Improvememory retentionVSAvoidmemory consolidation efficiency
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The system applies interventions periodically and discontinuously, triggered only when replay events are detected through EEG monitoring. Rather than continuous application, interventions are delivered at specific moments when target memories are naturally being replayed, maximizing enhancement effectiveness while minimizing disruption to other ongoing consolidation processes.

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The patent implements partial action by applying interventions only to specific memories that are currently being replayed, rather than enhancing all memories simultaneously. This selective approach ensures that resources are focused on target memories without creating interference effects that would result from attempting to consolidate multiple memories at once.

Inventive Principle:
Principle #16Partial or excessive action

3Extent of automation

If automated real-time EEG analysis is implemented, then precise control of memory interventions is achieved, but system complexity increases

Engineering Contradiction:
Improveintervention control automationVSAvoidsystem architecture complexity
Core Design Contradiction:
Extent of automationVSDevice complexity

Solution Approach 1:

The system employs self-service mechanisms through automated EEG decoding algorithms and a cognitive model-based predictive controller that independently analyze brain signals, identify replay events, and determine optimal intervention timing without human intervention. This automation reduces the need for complex manual monitoring and control systems, managing complexity through intelligent self-regulation.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent replaces manual, mechanical control systems with computational and information-processing-based systems. Instead of complex mechanical switches and manual monitoring, the system uses EEG decoding algorithms and predictive models to automatically control intervention delivery, substituting physical complexity with informational processing efficiency.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

4Measurement precision

If targeted memory interventions are applied, then recall accuracy of specific memories is improved, but the ability to enhance multiple memories simultaneously is reduced

Engineering Contradiction:
Improverecall accuracyVSAvoidnumber of memories enhanced
Core Design Contradiction:
Measurement precisionVSQuantity of substance

Solution Approach 1:

The system segments the memory enhancement process by identifying and targeting individual memories through separate replay detection and intervention triggering. Each memory is processed independently when its specific replay event is detected, allowing high recall accuracy for targeted memories while the system can sequentially handle multiple different memories throughout the sleep period through repeated cycles of detection and enhancement.

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS10796596B2Closed-loop intervention control system
Publication Date: 2020.10.06 HRL LAB
  • US10796596B2 patent drawing
  • US10796596B2 patent drawing
  • US10796596B2 patent drawing

AI summary

Described is a closed-loop intervention control system for memory consolidation in a subject. During operation, the system simulates memory changes of a first memory in a subject during waking encoding of the memory, and then while the subject is sleeping and coupled to an intervention system. Based on the simulated memory changes, the system predicts behavioral performance for the first memory, the behavioral performance being a probability that the first memory can be recalled on cue. The system can be used to control operation (e.g., turn on or off) of the intervention system with respect to the first memory based on the behavioral performance of the first memory determined by the simulation.