Mesh Disc Aneurysm Occlusion Device Design
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current endovascular treatments for saccular aneurysms, particularly wide-necked aneurysms, face challenges such as incomplete obliteration, thrombo-embolic events, parent artery occlusions, and high recurrence rates due to device failure, including collapse and migration of mesh occlusion devices, and the need for antiplatelet therapy with stent-assisted or flow-diverting techniques.
Innovation Solution
A modified mesh intrasaccular occlusion device with optional hydrogel is deployed across the aneurysm neck, secured by coils or other fillers, to provide enhanced neck coverage, prevent coil compaction, and reduce recurrence, using a disc-like structure that conforms to the aneurysm shape and is held in place by supplemental materials, minimizing the need for antiplatelet therapy.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If traditional wire coils are used to treat saccular aneurysms, then the treatment can be performed with simpler devices, but incomplete obliteration and high recurrence rates occur
Solution Approach 1:
The patent combines multiple functions into a single integrated mesh device: the mesh structure provides both occlusion (filling the aneurysm) and neck coverage (blocking the entrance), while also providing structural support to prevent coil compaction. This merging of functions eliminates the need for separate devices and achieves more complete obliteration with reduced recurrence rates.
Solution Approach 2:
The device uses a composite structure combining a mesh framework with integrated fillers or coatings. The mesh portion provides structural integrity and neck coverage, while the integrated fillers (such as coils, hydrogel, or other materials) provide occlusion. This composite approach allows the single device to achieve both structural support and complete filling, resolving the contradiction between simplicity and effectiveness.
2Reliability
If mesh occlusion devices are used to improve aneurysm filling, then obliteration completeness improves, but device collapse and migration into the aneurysm occur
Solution Approach 1:
The mesh device is designed with inherent structural features that prevent collapse before deployment occurs. The mesh configuration, wire diameter, and interwoven structure are engineered to maintain radial strength and prevent compaction during and after deployment, eliminating the need for additional support structures that could cause migration.
Solution Approach 2:
The device employs varying mesh densities and wire configurations in different regions: denser mesh or thicker wires at the neck region for structural support and migration prevention, and optimized mesh patterns in the body region for effective occlusion. This localized differentiation allows the device to maintain stability while achieving complete filling.
3Reliability
If stent-assisted or flow-diverting techniques are used to treat wide-necked aneurysms, then neck coverage improves, but the need for antiplatelet therapy increases
Solution Approach 1:
The patent extracts the flow-diverting function from separate stent devices and integrates it directly into the mesh occlusion device. The mesh structure itself provides neck coverage and flow diversion without requiring a separate stent framework, thereby eliminating the need for prolonged antiplatelet therapy while maintaining effective neck coverage.
Solution Approach 2:
The mesh device is designed as a temporary implant that provides acute neck coverage and flow diversion immediately upon deployment. Over time, thrombosis occludes the aneurysm and the mesh device becomes incorporated into the vessel wall, allowing removal or resorption. This temporary function eliminates the need for long-term antiplatelet therapy required by permanent stents.
4Manufacturing precision
If multiple catheters, balloons, or stents are used to treat wide-necked aneurysms, then coil positioning accuracy improves, but procedure complexity and risk of parent artery occlusion increase
Solution Approach 1:
The mesh device performs multiple functions simultaneously: it provides the scaffold for coil positioning, delivers the coils themselves, ensures accurate placement within the aneurysm, and prevents herniation into the parent artery. This multi-functionality in a single device achieves the positioning accuracy of complex multi-device systems without the associated complexity and risks.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The solution effectively reduces aneurysm recurrence, improves neck coverage, and decreases flow into the aneurysm, while maintaining the device in place without the need for antiplatelet therapy, addressing the limitations of existing treatments by providing immediate occlusion and enhanced stability.
Implementation Method 1
the outside surface of the disc facing into the aneurysm is lined with a non-biodegradable hydrogel, that when exposed to blood upon deployment, will swell over a prescribed time (10 minutes in the preferred embodiment of the present invention), to conform to the size and shape of the aneurysm, and fill and occlude said aneurysm
Data Source
AI summary
The present invention teaches the uses of a disc shaped mesh intrasaccular occlusion structure, with optional supplemental hydrogel, which is designed to implement an endovascular treatment to facilitate saccular aneurysm treatment while ameliorating or eliminating aneurysm recurrence.