Mesh Nebulizer Pressure Sensing for Accurate Inhalation Control

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Solution Overview

Problem

Conventional nebulizers suffer from incomplete medicament inhalation, residue, and user discomfort due to uneven airflow and structural inefficiencies, with dual pressure sensors being costly and prone to inaccuracy, and single pressure sensors failing in environmental variations.

Innovation Solution

A nebulization device with dual pressure sensors, one isolated from the airway to detect external pressure and the other adjacent to the airway to detect internal pressure, driving nebulization based on pressure difference without flow rate calculation, combined with a mesh for nebulization and structural features to reduce residue and discomfort.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional nebulizers use dual pressure sensors arranged inside the flow channel to achieve differential pressure calculation, then measurement precision is improved, but device complexity and cost increase

Engineering Contradiction:
Improveflow signal accuracyVSAvoidsensor arrangement complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent extracts one pressure sensor from the flow channel and places it outside, while keeping one sensor inside. This separation simplifies the overall sensor arrangement while maintaining the ability to measure differential pressure for flow detection, thereby reducing device complexity without sacrificing measurement precision.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent introduces a communication channel that connects the interior of the mouthpiece to the exterior environment, allowing the external pressure sensor to indirectly measure internal pressure conditions. This intermediary approach enables accurate flow measurement while keeping the sensor arrangement simpler and more cost-effective.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Device complexity

If conventional nebulizers use a single pressure sensor, then device complexity is reduced, but measurement precision deteriorates due to sensor deviation and inability to regress pressure values

Engineering Contradiction:
Improvesensor configuration simplicityVSAvoidpressure sensing accuracy
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The patent applies different sensor locations with different functional qualities - one sensor inside the mouthpiece for local pressure measurement and one sensor outside for reference pressure measurement. This local differentiation ensures accurate differential pressure calculation while maintaining overall system simplicity.

Inventive Principle:
Principle #3Local quality

3Device complexity

If conventional nebulizers have uneven airflow, then device complexity is reduced, but harmful factors increase due to strong pressure on user's lungs

Engineering Contradiction:
Improveairflow structure simplicityVSAvoidlung pressure discomfort
Core Design Contradiction:
Device complexityVSObject-affected harmful factors

Solution Approach 1:

The patent segments the airflow path into multiple controlled regions using internal partitions and multiple vents. This segmentation allows different parts of the airflow to be regulated independently, creating more uniform air distribution and reducing concentrated pressure on the user's lungs while maintaining structural simplicity.

Inventive Principle:
Principle #1Segmentation

4Device complexity

If conventional nebulizers lack additional structures for complete inhalation, then device complexity is reduced, but loss of substance increases due to medicament residue and waste

Engineering Contradiction:
Improvestructural simplicityVSAvoidmedicament residue
Core Design Contradiction:
Device complexityVSLoss of substance

Solution Approach 1:

The patent incorporates internal partitions and multiple vents that are pre-configured to guide and optimize airflow patterns before the user inhalation occurs. This preliminary structural arrangement ensures that medicament-laden air is efficiently directed toward the user's lungs, maximizing medicament delivery and minimizing residue and waste.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enhances medicament utilization, reduces residue, and improves user comfort by stabilizing airflow, while being more cost-effective and accurate than conventional devices.

Implementation Method 1

a first pressure sensor disposed inside the nebulization medicament delivery device and to be air-tightly isolated from the airway, and configured to detect external air pressure outside the nebulization medicament delivery device

Methodology Applied
Scientific EffectPressure detection:

Implementation Method 2

a second pressure sensor disposed adjacent to the airway or within the airway, and configured to detect air pressure inside the airway

Methodology Applied
Scientific EffectPressure detection:

Implementation Method 3

the controller drives the nebulization module to perform nebulization based on air pressure difference between the external air pressure and the air pressure inside the airway

Methodology Applied
Scientific EffectPressure difference driven flow: Pressure Gradient

Implementation Method 4

the detection module detects the pressure applied by the medicament onto the mesh through the piezoelectric element to convert the pressure into a voltage signal or a current signal

Methodology Applied
Scientific EffectPiezoelectric effect: Piezoelectric Effect

Data Source

PatentEP4520374B1Nebulization medicament delivery device
Publication Date: 2026.05.13 DELBIO
  • EP4520374B1 patent drawingFigure 1
  • EP4520374B1 patent drawingFigure 2
  • EP4520374B1 patent drawingFigure 3

AI summary

A nebulization medicament delivery device (1) is provided, which includes a mouthpiece opening (10); an airway (11); at least one first vent (12) configured to introduce external air into the airway (11), wherein the mouthpiece opening (10) is in communication with the at least one first vent (12) through the airway (11); a nebulization module (13) including a mesh and configured for nebulization; a first pressure sensor (14) disposed inside the nebulization medicament delivery device (1) and to be air-tightly isolated from the airway (11), and configured to detect external air pressure outside the nebulization medicament delivery device (1); a second pressure sensor (15) disposed adjacent to the airway (11) or within the airway (11), and configured to detect air pressure inside the airway (11); and a controller, which drives the nebulization module (13) to perform nebulization based on air pressure difference between the external air pressure and the air pressure inside the airway (11).