Expandable Mesh Reservoir for Interstitial Medication Delivery

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Solution Overview

Problem

Current parenteral administration methods, such as intravenous (IV) fluid and medication delivery, require skilled medical personnel, are time-consuming, and can lead to complications like vein sclerosis and scar tissue formation, which limits their effectiveness and accessibility, especially in mass casualty situations or for long-term treatments.

Innovation Solution

An expandable reservoir made of mesh with a stylet-guided catheter and a self-inflating balloon mechanism for secure placement, allowing for the administration of fluids and medications into interstitial fluid, compatible with both proprietary and commercially available infusion systems, and drug-eluting capabilities to prevent scar tissue formation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If intravenous (IV) administration is used for fluid and medication delivery, then effective drug delivery is achieved, but skilled medical personnel are required and installation time increases

Engineering Contradiction:
Improveeffective drug deliveryVSAvoidrequires skilled medical personnel
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The expandable reservoir system is designed to be self-securing through tissue ingrowth and fibrosis formation, eliminating the need for continuous skilled personnel intervention. The device autonomously anchors itself in the interstitial space, allowing patients to receive long-term treatment without requiring qualified medical staff for maintenance or monitoring of the access site.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The reservoir acts as an intermediary device between the external infusion system and the patient's interstitial fluid space. It provides a stable, long-term access point that mediates the connection between temporary external catheters and the body's internal fluid compartments, enabling sustained medication delivery without direct IV vein access.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Duration of action of moving object

If prolonged IV administration is used, then continuous medication delivery is achieved, but vein sclerosis and complications occur

Engineering Contradiction:
Improvecontinuous medication deliveryVSAvoidvein sclerosis and complications
Core Design Contradiction:
Duration of action of moving objectVSObject-affected harmful factors

Solution Approach 1:

The invention extracts the medication delivery function from the venous system and relocates it to the interstitial fluid space. By placing the reservoir in the subcutaneous or interstitial tissue rather than in veins, the harmful effects of prolonged IV access such as vein sclerosis, phlebitis, and thrombosis are avoided while maintaining continuous medication delivery capability.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

Instead of delivering medications through the conventional IV route into veins, the system inverts the approach by delivering medications into the interstitial fluid space where they can then diffuse into the bloodstream. This reverse routing eliminates direct venous contact and associated complications while achieving the same therapeutic effect.

Inventive Principle:
Principle #13The other way round (Inversion)

3Duration of action of moving object

If central vein placement is used for prolonged treatment, then medication delivery is maintained, but immediate risks and late complications increase

Engineering Contradiction:
Improveprolonged treatmentVSAvoidimmediate risks and late complications
Core Design Contradiction:
Duration of action of moving objectVSObject-affected harmful factors

Solution Approach 1:

The reservoir system uses a disposable, pre-sterilized access device that is implanted once and left in place for prolonged treatment. The single-use nature of the reservoir eliminates repeated punctures and infections associated with temporary IV access, while its placement in interstitial tissue rather than central veins avoids the serious complications of central line placement such as air embolism, arrhythmia, and catheter malposition.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

4Ease of operation

If more medical personnel are deployed for MCI treatment, then patient care quality improves, but resource availability decreases

Engineering Contradiction:
Improvepatient care qualityVSAvoidresource availability
Core Design Contradiction:
Ease of operationVSProductivity

Solution Approach 1:

The reservoir system enables preliminary establishment of long-term access that does not require continuous skilled personnel presence. Once the reservoir is implanted by a single healthcare provider, it maintains itself through tissue ingrowth and can be refilled or adjusted with minimal intervention, allowing one provider to effectively manage multiple patients simultaneously and improving overall system productivity during mass casualty incidents.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This solution reduces the need for skilled personnel, decreases installation and maintenance time, minimizes complications, and enables precise dose administration, making it suitable for various medical applications, including mass casualty scenarios and long-term treatments, while being cost-effective and improving treatment compliance.

Implementation Method 1

an expandable reservoir made from mesh (1) and a stylet guided catheter (2)

Methodology Applied
Scientific EffectExpandable reservoir:

Implementation Method 2

Drug-eluting reservoirs slowly emit medication that prevents scar formation

Methodology Applied
Scientific EffectDrug-eluting:

Implementation Method 3

The implantable medication pump will administer medication into the open space that the reservoir created

Methodology Applied
Scientific EffectPump: Pump

Data Source

PatentUS20220296809A1Parenteral administration of medications, fluids, and nutrition
Publication Date: 2022.09.22 KATSNELSON ILANA
  • US20220296809A1 patent drawing
  • US20220296809A1 patent drawing
  • US20220296809A1 patent drawing

AI summary

The present invention relates to the delivery of therapeutic agents into interstitial fluid and designed to substitute other forms of parenteral administration of fluid and medications when it is appropriate. The invention features an expandable reservoir made from mesh and a stylet guided catheter. The innovation of proposed catheter comprises to a catheter for administration of fluid and medications and a mechanism that safely secures the catheter inside the reservoir in order to prevent it from accidental dislodging. One of the ways to secure catheter is self-inflated balloon on its proximal end of the catheter.