Multi-Solvent Meta-Diamide Formulation for Mosquito Control

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Solution Overview

Problem

Current insecticidal compositions used for controlling adult mosquito populations, particularly through Ultra-Low Volume (ULV) technology, face challenges in persistence and effectiveness due to limited solvent solubility of meta-diamides and inefficient droplet distribution, which affects their ability to contact and kill mosquitoes effectively.

Innovation Solution

The development of insecticidal compositions that include meta-diamides as active ingredients, combined with a multi-solvent system comprising a tricarboxylate solvent and a polyalkylene solvent, along with a surfactant, to enhance solubility and persistence in the air column, allowing for effective contact with flying mosquitoes.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a single solvent system is used with meta-diamide, then the formulation is simple, but the solubility and persistence of the active ingredient are insufficient

Engineering Contradiction:
Improvepersistence in air columnVSAvoidsolvent system complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent uses a composite solvent system comprising multiple solvents (e.g., citrate ester, carbonate, and alcohol) instead of a single solvent. This composite approach enhances the solubility of meta-diamide and improves aerosol persistence in the air column, resolving the contradiction between formulation simplicity and performance reliability.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent optimizes the ratios and concentrations of different solvents in the mixture to achieve optimal solubility and persistence. By adjusting compositional parameters of the solvent system, the formulation achieves enhanced reliability without excessive complexity.

Inventive Principle:
Principle #35Parameter changes

2Productivity

If conventional solvents are used, then the formulation is easy to manufacture, but the droplet distribution and contact efficiency with mosquitoes are poor

Engineering Contradiction:
Improvemosquito control effectivenessVSAvoidformulation complexity
Core Design Contradiction:
ProductivityVSEase of manufacture

Solution Approach 1:

The patent introduces surfactants as intermediary substances that facilitate better droplet distribution and contact with mosquito surfaces. The surfactant acts as a mediator between the solvent system and the target organism, enhancing contact efficiency without significantly complicating the manufacturing process.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The combination of multiple solvents and surfactants creates a composite formulation that improves droplet characteristics and contact efficiency. This composite approach enhances productivity in mosquito control while maintaining reasonable ease of manufacture through standardized formulation processes.

Inventive Principle:
Principle #40Composite materials

3Reliability

If meta-diamide is used as active ingredient, then the insecticidal activity is high, but the solubility in conventional solvents is limited

Engineering Contradiction:
Improveinsecticidal efficacyVSAvoidsolubility of active ingredient
Core Design Contradiction:
ReliabilityVSQuantity of substance

Solution Approach 1:

The patent employs a composite solvent system with multiple components (citrate esters, carbonates, alcohols) that collectively provide enhanced solubility for meta-diamide. This composite solvent approach maintains high insecticidal efficacy while overcoming the solubility limitations of conventional single solvents.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent adjusts the compositional parameters of the solvent system, including the types and ratios of solvents, to optimize the solubility of meta-diamide. By changing the chemical environment through parameter optimization, the formulation achieves both high solubility and maintained insecticidal activity.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The proposed compositions demonstrate high mortality rates of at least 70% against Aedes, Culex, and Anopheles mosquitoes within 24-48 hours, with field trials showing average mortality rates of 98.3% at 72 hours, indicating improved persistence and effectiveness in mosquito control.

Implementation Method 1

a solvent system including a tricarboxylate solvent and a second solvent

Methodology Applied
Scientific EffectSolubility enhancement through multi-solvent system: Solvation

Implementation Method 2

and a surfactant

Methodology Applied
Scientific EffectSurface tension reduction: Surfactant

Implementation Method 3

emitting an ultra-low volume (ULV) insecticidal composition... allowing for effective contact with flying mosquitoes

Methodology Applied
Scientific EffectAerosol formation and persistence: Aerosol

Data Source

PatentUS20240215580A1Multi-solvent insecticidal compositions including meta-diamide
Publication Date: 2024.07.04 CLARKE MOSQUITO CONTROL PRODUCTS INC
  • US20240215580A1 patent drawing
  • US20240215580A1 patent drawing
  • US20240215580A1 patent drawing

AI summary

Insecticidal compositions may include an active ingredient, a solvent system, and a surfactant. The active ingredient may include a meta-diamide. The solvent system may include a tricarboxylate solvent and a second solvent. The surfactant may be an alkoxylated alcohol. Methods for insect control may include contacting a population of insects with an insecticidal composition. In some aspects, insecticidal compositions are particularly suited for use against mosquitos.