Meta-Learning Medical Image Segmentation Model

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Solution Overview

Problem

Conventional medical image segmentation using artificial neural networks faces challenges in effectively segmenting metastatic brain cancers due to limited reliable datasets, leading to poor performance in distinguishing between primary and metastatic cancers, and requires extensive additional data for fine-tuning, making it impractical for automation.

Innovation Solution

A medical image segmentation deep-learning model generation apparatus and method that utilizes meta-learning and active learning techniques to generate a training dataset by sampling good and bad task data, updating weights, and repeating primary and secondary learning processes to expand the model's capability from primary to metastatic cancer segmentation without losing existing pattern recognition.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional fine-tuning method is used to segment metastatic cancer, then segmentation capability for metastatic cancer can be improved, but extensive additional data is required making the method impractical

Engineering Contradiction:
Improvesegmentation capabilityVSAvoiddata amount
Core Design Contradiction:
ReliabilityVSQuantity of substance

Solution Approach 1:

The system performs preliminary segmentation using an original model to generate predicted segmentation results, which are then used to create synthetic training data. This preliminary action enables the generation of training datasets without requiring extensive additional annotated data, resolving the contradiction between improving segmentation capability and reducing data requirements.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system creates copies of existing training data by generating synthetic datasets through the original model's predictions. Instead of collecting new annotated data, the system copies and transforms existing data patterns to create new training examples, thereby improving metastatic cancer segmentation without requiring extensive additional data.

Inventive Principle:
Principle #26Copying

2Measurement precision

If artificial neural network is trained based on one type of cancer, then segmentation performance for that specific cancer is improved, but the model cannot segment other types of cancers well

Engineering Contradiction:
Improvesegmentation accuracyVSAvoiddisease type coverage
Core Design Contradiction:
Measurement precisionVSAdaptability or versatility

Solution Approach 1:

The system creates a universal training framework that can handle multiple cancer types. By generating synthetic training data that incorporates characteristics of different cancer types and using a unified model architecture, the system achieves both high segmentation accuracy for specific cancers and broad adaptability across different disease types.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The system adapts to different cancer types by changing training parameters and data characteristics rather than creating entirely new models. Through parameter adjustments in the synthetic data generation process and iterative retraining, the model maintains high accuracy across multiple cancer types, resolving the contradiction between specialization and versatility.

Inventive Principle:
Principle #35Parameter changes

3Adaptability or versatility

If original medical image segmentation model is used to generate training data, then new patterns can be learned, but capability for previously well-segmented patterns may be lost

Engineering Contradiction:
Improvenew pattern recognitionVSAvoidexisting pattern performance
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

The system implements feedback through iterative retraining where the model's own predictions are evaluated and used to generate targeted synthetic training data. This feedback loop ensures that the model continuously improves at new patterns while maintaining performance on existing patterns, as the training process reinforces both old and new capabilities rather than replacing them.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system maintains continuity of useful action by performing iterative retraining that continuously reinforces both existing and new segmentation capabilities. Rather than discrete model replacements, the continuous training process ensures that performance on well-segmented patterns is maintained while gradually acquiring new pattern recognition abilities.

Inventive Principle:
Principle #20Continuity of useful action

Data Source

PatentUS11321589B2Apparatus and method for generating medical image segmentation deep-learning model, and medical image segmentation deep-learning model generated therefrom
Publication Date: 2022.05.03 HODOOAI LAB INC
  • US11321589B2 patent drawing
  • US11321589B2 patent drawing
  • US11321589B2 patent drawing

AI summary

There is provided a medical image segmentation deep-learning model generation apparatus including a training data generation/allocation unit configured to generate a training dataset through a segmentation result value acquired by inputting a given medical image to an original medical image segmentation deep-learning model and a learning control unit configured to acquire temporary weights using output data corresponding to primary learning by inputting good task data and bad task data sampled from primary learning training datasets to the medical image segmentation deep-learning model and configured to update weights by adding gradients acquired using weights acquired using output data corresponding to secondary learning by inputting good task data and bad task data sampled from secondary learning training datasets to the medical image segmentation deep-learning model, wherein the primary learning and the secondary learning are repeated.