Meta-surface Biosensor Eliminates Spectrometer for Biomaterial Detection
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Solution Overview
Problem
Existing biosensing methods require precise optical spectrometers for color discrimination and angle change measurements, making them cumbersome and inefficient for diagnosing and detecting biomaterials.
Innovation Solution
A biosensor system incorporating meta-optical elements and artificial intelligence, where meta-surface elements convert incident light into structured beams or focus it to specific points, and AI models analyze the pattern of output light to determine the presence and amount of biomaterials, eliminating the need for large optical components.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If antigen-antibody immunoassay with color discrimination is used, then biosensing capability is achieved, but precise optical spectrometer is required which increases device complexity
Solution Approach 1:
The patent replaces the mechanical/optical spectrometer system with a meta-surface optical element that performs wavelength multiplexing functions. The meta-surface element manipulates light waves directly through its nanostructure array, substituting the need for complex mechanical spectrometric measurement systems while maintaining biosensing capability.
Solution Approach 2:
The patent changes the optical parameters by using a meta-surface element with specific phase profiles that disperse different wavelengths at different angles. This parameter change in light propagation characteristics enables spectral information encoding without requiring a traditional spectrometer, thus reducing device complexity while preserving biosensing functionality.
2Reliability
If surface plasmon resonance technology is used, then biosensing is achieved, but precise spectrum spectrometer is needed to measure angle change which increases device complexity
Solution Approach 1:
The patent substitutes the spectrum spectrometer measurement system with a meta-surface element that inherently encodes spectral information in the spatial distribution of output light. The meta-surface element performs the function of wavelength separation and detection without requiring external spectrometric measurement equipment, thereby reducing device complexity while maintaining biosensing capability.
Solution Approach 2:
The patent creates a spatial copy of spectral information through the meta-surface element's wavelength multiplexing function. Different wavelengths are mapped to different spatial positions in the output light pattern, allowing spectral data to be captured and analyzed without a traditional spectrometer, thus eliminating the need for complex measurement equipment while preserving biosensing functionality.
3Ease of operation
If traditional optical components are used for light manipulation, then light control is achieved, but device size and complexity increase
Solution Approach 1:
The patent uses a thin meta-surface optical element to perform complex light manipulation functions that traditionally required bulky optical components. The meta-surface element's thin-film structure with nano-scale patterns enables precise wavefront control, beam shaping, and wavelength multiplexing in a compact form factor, thus maintaining light control capability while dramatically reducing device size and complexity.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach simplifies biomaterial detection by using camera technology and AI, replacing complex optical components and enabling efficient acquisition of biomaterial information without the need for precise spectrometers.
Implementation Method 1
the first meta surface element may include a meta surface element that converts the incident light into a structured beam, and the second meta surface element may include a meta lens element that focuses the incident light to a specific point
Data Source
AI summary
A method performed by a biosystem comprising a biosensor kit and a biosensor kit analyzer is disclosed. According to an embodiment of the present disclosure, a method performed by a biosystem may include injecting a solution sample into the biosensor kit, the biosensor kit including a biosensor equipped with at least one metasurface element, based on the biosensor kit being inserted into the biosensor kit analyzer, injecting incident light into a lower region of the at least one metasurface element by the biosensor kit analyzer; obtaining a pattern image of output light changed by the at least one meta-surface element; obtaining, by the biosensor kit analyzer, a presence or absence and amount of biomaterial on the solution sample by inputting the pattern image into a pre-trained artificial intelligence model; and displaying the presence or absence and amount of the biomaterial on the solution sample.