Personal Metabolic Model for Predictive Blood Glucose Response

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Solution Overview

Problem

Existing blood glucose monitoring methods only allow for reactive management of blood sugar levels, primarily benefiting individuals with diabetes, and do not facilitate proactive control or monitoring for general health management.

Innovation Solution

A computer-implemented method and system that simulates a user's metabolic system using a personalized digital model, predicting blood glucose responses to food intake and generating recommendations for improved glucose management, utilizing machine learning models trained with user data and real-time feedback.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Loss of time

If traditional blood glucose monitoring methods are used, then blood glucose levels can be measured, but only reactive management is possible requiring regular testing

Engineering Contradiction:
Improvetime for blood glucose managementVSAvoidease of blood glucose management
Core Design Contradiction:
Loss of timeVSEase of operation

Solution Approach 1:

The system performs preliminary action by predicting future blood glucose levels before they actually occur. The metabolic response model forecasts glucose excursions in advance of food intake events, enabling users to take preventive action rather than reacting after glucose levels have already changed. This eliminates the need for frequent reactive testing.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system implements feedback by continuously monitoring actual glucose measurements and using them to refine and retrain the metabolic response model. This closed-loop feedback mechanism improves prediction accuracy over time while reducing the frequency of required measurements, thereby decreasing testing burden while maintaining or improving management quality.

Inventive Principle:
Principle #23Feedback

2Loss of information

If reactive blood glucose testing is performed, then current glucose levels can be identified, but proactive control is not enabled

Engineering Contradiction:
Improveinformation about glucose responseVSAvoidefficiency of glucose management
Core Design Contradiction:
Loss of informationVSProductivity

Solution Approach 1:

The system generates predictions of glucose responses to various food intake scenarios before the user actually consumes the food. This preliminary information provision enables proactive decision-making about dietary choices, allowing users to prevent unwanted glucose excursions rather than merely responding to them after occurrence.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The metabolic response model acts as an intermediary between food intake and glucose measurement. Instead of directly measuring glucose and reacting, the model simulates the metabolic process and provides predictive information about future glucose levels, enabling intermediate preventive actions.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Reliability

If regular blood glucose testing is required, then glucose management can be performed, but user burden increases

Engineering Contradiction:
Improvereliability of glucose managementVSAvoidcomplexity of monitoring system
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system creates a digital copy or virtual model of the user's metabolic system. This metabolic response model replicates the complex physiological glucose regulation process, allowing predictions to be made without physically measuring glucose repeatedly. The virtual model captures individual metabolic characteristics while eliminating the need for frequent physical testing.

Inventive Principle:
Principle #26Copying

Solution Approach 2:

The system transitions from measuring multiple glucose parameters over time to estimating a single predictive parameter (future glucose level) based on food intake characteristics. This parameter transformation reduces the frequency and complexity of measurements while maintaining reliable glucose management through the predictive capability.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS20260020784A1Monitoring metabolic response
Publication Date: 2026.01.22 GLUCOSE REPUBLIC LTD
  • US20260020784A1 patent drawing
  • US20260020784A1 patent drawing
  • US20260020784A1 patent drawing

AI summary

Simulating a user's metabolic system and predicting a blood glucose response based on a specified food intake event includes receiving characteristic data representative of specified user characteristics, converting said characteristic data into object data and utilising said object data and a master model to generate a personal digital model representative of said user's metabolic system, receiving food intake data representative of a said specified food intake event, obtaining or generating current glucose data for said user, inputting said food intake data to said personal digital model, and generating, using said personal digital model, a simulation of said user's metabolic system in response to said food intake data and generating a predicted blood glucose response to said specified food intake event, outputting data representative of said predicted blood glucose response, and utilising said data representative of said predicted blood glucose response to retrain said master model and said personal digital model.