Methane Fermentation Bioreactor Heat Removal via CO2 Stripping

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Solution Overview

Problem

Current bioprocesses for producing polyhydroxyalkanoates (PHA) from methane-containing gases face challenges due to low methanotroph densities and high heat generation, resulting in low productivity and high costs, making PHA more expensive than conventional polymers.

Innovation Solution

The process involves achieving high methanotroph densities by optimizing methane and oxygen mass transfer rates and integrating heat removal through carbon dioxide stripping and evaporation, allowing for higher productivity while maintaining suitable temperatures.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If high density of methanotrophs is achieved per unit of bioreactor volume, then PHA productivity per unit volume is improved, but heat generation increases making temperature control difficult

Engineering Contradiction:
ImprovePHA productivity per unit volumeVSAvoidtemperature control
Core Design Contradiction:
ProductivityVSTemperature

Solution Approach 1:

The patent extracts heat from the bioreactor system by removing carbon dioxide through stripping and utilizing evaporation of water. This separates the heat removal function from the biological conversion process, allowing high cell densities to be maintained without excessive heat accumulation that would otherwise limit productivity.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent changes the physical state and composition parameters of the aqueous medium by continuously stripping carbon dioxide and controlling water evaporation. These parameter changes enable the system to dissipate heat effectively while maintaining optimal conditions for high methanotroph density and PHA production.

Inventive Principle:
Principle #35Parameter changes

2Quantity of substance

If high mass transfer rates of methane are achieved, then methanotroph density is improved, but heat generation and carbon dioxide production increase

Engineering Contradiction:
Improvemethanotroph densityVSAvoidheat generation and carbon dioxide production
Core Design Contradiction:
Quantity of substanceVSObject-generated harmful factors

Solution Approach 1:

The patent converts the harmful effects of carbon dioxide accumulation and heat generation into beneficial processes. Carbon dioxide stripping is used to remove excess CO2 while simultaneously removing heat through the evaporation of water. The system transforms what would be waste products into mechanisms for thermal management and mass transfer optimization.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Solution Approach 2:

The patent introduces carbon dioxide stripping as an intermediary process between methane consumption and PHA production. This intermediary step manages the byproducts (CO2 and heat) generated by high methanotroph activity, allowing the system to maintain high cell densities without being limited by harmful accumulations.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Productivity

If carbon dioxide is removed from aqueous medium through stripping, then mass transfer rates of methane and oxygen are improved, but energy consumption increases

Engineering Contradiction:
Improvemass transfer rateVSAvoidcooling cost
Core Design Contradiction:
ProductivityVSLoss of energy

Solution Approach 1:

The patent merges the carbon dioxide removal function with the heat removal function into a single integrated process. By stripping CO2 and utilizing evaporation simultaneously, the system achieves both mass transfer improvement and thermal management in one operation, rather than requiring separate energy-intensive cooling and gas stripping systems.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enables higher PHA productivity per unit volume of bioreactor with reduced cooling costs, making the production of PHA more economically viable and competitive with conventional polymers.

Implementation Method 1

The fermentation of methane by methanotrophs is well known

Methodology Applied
Scientific EffectFermentation: Fermentation

Implementation Method 2

Since water is also formed during the metabolic oxidation of methane to carbon dioxide

Methodology Applied
Scientific EffectMetabolic oxidation: Oxidation

Implementation Method 3

during the contact with the stripping gas, the evaporation of carbon dioxide and water from the withdrawn aqueous medium results in cooling the aqueous medium

Methodology Applied
Scientific EffectEvaporation: Evaporation

Implementation Method 4

the evaporation of carbon dioxide and water from the withdrawn aqueous medium results in cooling the aqueous medium

Methodology Applied
Scientific EffectEvaporative cooling: Evaporative Cooler

Implementation Method 5

a portion of aqueous medium containing carbon dioxide generated by the methanotrophs is withdrawn from the reaction zone and contacted with a stripping gas to remove dissolved carbon dioxide from the withdrawn aqueous medium

Methodology Applied
Scientific EffectGas stripping: Sparging

Implementation Method 6

These high mass transfer rates support high methanotroph densities

Methodology Applied
Scientific EffectMass transfer: Diffusion

Data Source

PatentEP3625327B1High productivity methane fermentation processes
Publication Date: 2023.12.27 MANGO MATERIALS INC
  • EP3625327B1 patent drawingFigure 1

AI summary

Processes are provided for enhancing the productivity of fermenters during the metabolic conversion of methane-containing gases to products containing polyhydroxyalkanoate, which products can be used to make, for instance, animal feed or biodegradable, polymeric articles. The processes involve one or both of attenuating the heat generated to grow a population of microorganisms and removal of heat during the fermentation by removal of carbon dioxide.