MFF6771 Maize Inbred Line Segmentation and Hybridization

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

The challenge in corn breeding is to develop maize plants that combine high yield, disease resistance, and adaptability to various environmental conditions, while also maintaining the genetic stability and uniformity required for hybrid seed production.

Innovation Solution

The development of the maize variety MFF6771, which includes specific traits such as increased water stress resistance, waxy starch, male sterility, and resistance to diseases and pests, achieved through traditional breeding methods and potentially enhanced by genetic markers and transgenic approaches.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If inbred maize lines are used for hybrid seed production, then genetic uniformity and reproducibility are improved, but plant vigor and seed yield are worsened

Engineering Contradiction:
Improvegenetic uniformityVSAvoidseed yield
Core Design Contradiction:
Stability of the object's compositionVSProductivity

Solution Approach 1:

The breeding program segments the development process into distinct phases: creating highly homozygous inbred lines through multiple generations of self-pollination for genetic uniformity, then using these inbreds as parents to produce hybrid F1 generation that exhibits heterosis and high vigor. This segmentation allows each generation to serve its specific purpose without compromise.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Instead of using vigorous heterozygous plants directly for seed production, the program inverts the approach by first creating homozygous inbreds (which are less vigorous but genetically uniform) and then crossing them to produce the vigorous hybrid F1 generation. The weakness of inbreds is inverted into a strength through hybridization.

Inventive Principle:
Principle #13The other way round (Inversion)

2Adaptability or versatility

If multiple desirable traits are combined in a single variety, then adaptability and resistance are improved, but breeding complexity and time are worsened

Engineering Contradiction:
Improveadaptability to environmental conditionsVSAvoidbreeding program complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The program merges multiple desirable traits from different parental inbred lines into a single hybrid variety. By selecting parents with complementary traits (disease resistance, abiotic stress tolerance, yield potential) and crossing them, the hybrid offspring combines all these traits in one package, achieving broad adaptability without managing multiple separate varieties.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The program performs preliminary selection and characterization of parental inbred lines for specific traits before hybridization. Genetic markers are used early in the breeding process to identify and select parents carrying desired traits, so that when hybrids are produced, they inherit predetermined combinations of resistance and adaptability traits, reducing later breeding complexity.

Inventive Principle:
Principle #10Preliminary action

3Stability of the object's composition

If traditional breeding methods are used, then genetic stability is improved, but breeding efficiency and speed are worsened

Engineering Contradiction:
Improvegenetic stabilityVSAvoidbreeding speed
Core Design Contradiction:
Stability of the object's compositionVSProductivity

Solution Approach 1:

The program incorporates molecular marker-based selection as a feedback mechanism throughout the breeding process. Genetic markers provide real-time information about the presence and inheritance of desired traits, allowing breeders to make informed selection decisions at each generation. This feedback accelerates the breeding process while maintaining genetic stability by ensuring accurate tracking of target alleles.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The program substitutes mechanical/phenotypic selection methods with molecular marker-based selection. Instead of relying solely on visual observation and manual selection of plant traits, DNA markers provide molecular-level detection of genetic composition, replacing traditional mechanical breeding approaches with a more precise and efficient molecular system that maintains genetic integrity while accelerating progress.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Data Source

PatentUS12302827B2Variety corn line MFF6771
Publication Date: 2025.05.20 SYNGENTA CROP PROTECITON AG

AI summary

The present invention provides an inbred corn line designated MFF6771, methods for producing a corn plant by crossing plants of the inbred line MFF6771 with plants of another corn plant. The invention further encompasses all parts of inbred corn line MFF6771, including culturable cells. Additionally provided herein are methods for introducing transgenes into inbred corn line MFF6771, and plants produced according to these methods.