Micro-lipo Needle with Vacuum Interlock and Concentric Seal

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Solution Overview

Problem

Existing adipose tissue grafting and transfer methods face challenges such as necrosis, absorption by the body, infection, calcifications, scarring, inconsistent engraftment, and lack of durability due to inadequate neovascularization and necrosis of transplanted tissue.

Innovation Solution

The development of a micro-lipo needle device with a vacuum interlock element, a matched set of needle and cannula forming a concentric seal, and a mechanism to safeguard the needle's travel, allowing for safe and controlled liposuction and tissue harvesting. The device is designed for one-time use and includes a tissue filtration/purification system for improved graft quality.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional liposuction methods are used to harvest adipose tissue, then tissue can be obtained, but needle insertion safety is compromised and uncontrolled leakage occurs

Engineering Contradiction:
Improvesafety of needle insertionVSAvoiduncontrolled leakage
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The needle's travel is pre-limited by the mechanism before insertion occurs. The safeguard mechanism ensures the needle can only penetrate to a predetermined safe depth, preventing over-insertion into fat tissue before the actual harvesting action begins.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent introduces an intermediary mechanism between the needle and the fat tissue that controls and regulates the insertion process. This intermediate safeguard mechanism acts as a mediator that allows controlled access while preventing harmful uncontrolled leakage and over-penetration.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Ease of manufacture

If adipose tissue is harvested and mixed with liquid (water, blood, tumescent solution), then tissue can be processed, but volume is lost due to rapid absorption of liquid by the body

Engineering Contradiction:
Improvetissue processing capabilityVSAvoidgraft volume retention
Core Design Contradiction:
Ease of manufactureVSLoss of substance

Solution Approach 1:

The tissue filtration/purification system extracts and removes excess liquid from the harvested adipose tissue. This extraction process separates the useful adipose tissue components from the harmful excess liquid that would otherwise be rapidly absorbed by the body, thereby preserving graft volume.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The filtration system changes the physical parameters of the harvested tissue by adjusting the liquid-to-tissue ratio. By removing excess liquid through filtration, the system optimizes the tissue's physical state for transplantation, improving volume retention while maintaining processability.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If concentrated populations of adipose-derived regenerative cells are added to improve graft retention and vascularization, then graft quality improves, but processing complexity and equipment requirements increase

Engineering Contradiction:
Improvegraft retention and vascularizationVSAvoidprocessing equipment and specialized clinicians
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent combines the harvesting, filtration, and concentration functions into a single integrated device system. By merging these previously separate processing steps into one unified apparatus, the system achieves improved graft retention and vascularization without requiring multiple separate pieces of equipment or highly specialized processing procedures.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The micro-lipo needle device with integrated filtration system performs multiple functions: harvesting adipose tissue, filtering out excess liquid, and concentrating regenerative cells. This multi-functional approach eliminates the need for separate specialized equipment for each processing step, reducing overall device complexity while maintaining improved graft outcomes.

Inventive Principle:
Principle #6Universality (Multi-functionality)

4Object-affected harmful factors

If closed sterile fluid pathway is used to reduce infection risk, then safety improves, but device complexity increases

Engineering Contradiction:
Improveinfection riskVSAvoidsterile fluid pathway system
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The device employs a nested structure where the needle is inserted through the inner portion of the cannula, creating a concentric seal. This nested arrangement inherently creates a closed sterile fluid pathway without requiring additional complex external sealing systems, as the nested geometry itself provides the sterile barrier.

Inventive Principle:
Principle #7Nested doll (Nesting)

Solution Approach 2:

The concentric seal formed by the nested needle and cannula acts as a flexible thin-film barrier that maintains sterile conditions. This flexible sealing approach provides effective infection prevention without the rigidity and complexity of hard sealed systems, allowing the closed pathway to adapt to tissue contours while maintaining sterility.

Inventive Principle:
Principle #30Flexible shells and thin films

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The micro-lipo needle device enhances the safety and efficacy of adipose tissue harvesting by preventing needle insertion into fat tissue, reducing leakage, and ensuring controlled vacuum conditions, thereby improving graft retention, vascularization, and overall surgical outcomes.

Implementation Method 1

a main housing providing a cavity, which cavity being communicateble with a vacuum source such that when the main housing is placed on an area of a body the vacuum source generates a degree of vacuum to cause a volume of skin and fat to be lifted so as to fill up the cavity

Methodology Applied
Scientific EffectVacuum: Vacuum

Implementation Method 2

a matched set of needle and cannula forming a concentric seal, limiting leakage

Methodology Applied
Scientific EffectConcentric seal:

Data Source

PatentEP3614930B1Micro-lipo needle devices
Publication Date: 2025.04.23 AURASTEM LLC
  • EP3614930B1 patent drawingFigure 1A
  • EP3614930B1 patent drawingFigure 1B
  • EP3614930B1 patent drawingFigure 2A

AI summary

Embodiments of the present invention disclose micro-lipo needle device and methods of making and using the same.