Micro-reactor Scaling via Hydraulic Diameter Calculation

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Solution Overview

Problem

Existing micro-reactor technologies face challenges in achieving a target volumetric flow-rate for chemical reactions, particularly type B reactions, which are rapid and temperature sensitive, as scaling up or down requires adjustments in reactor design and flow dynamics to maintain reaction conditions, often leading to inefficient mixing and increased complexity in controlling reaction parameters.

Innovation Solution

A method to manufacture a target micro-reactor by calculating the smallest hydraulic diameter based on the relationship dh2 = dh1 * (f2/f1)^(3-n)/(7-n), where dh1 is the standard reactor's hydraulic diameter, f1 is the standard volumetric flow-rate, f2 is the target flow-rate, and n is a non-integer between 0 and 1, to optimize energy input and mixing efficiency in the mixing zone, while maintaining similar flow conditions in the retention zone.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If the reactor is sized-up to increase volumetric flow-rate, then productivity is improved, but fluid dynamics change resulting in altered reaction conditions

Engineering Contradiction:
Improvevolumetric flow-rateVSAvoidreaction conditions stability
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent applies parameter changes by systematically adjusting geometric parameters of the flow channel system according to specific scaling relationships. The cross-sectional area is increased while maintaining the aspect ratio, and the channel length is extended proportionally to the area increase. This controlled parameter change allows scaling up the reactor to higher volumetric flow-rates while preserving the fluid dynamics and reaction conditions through mathematically defined relationships between geometric parameters.

Inventive Principle:
Principle #35Parameter changes

2Productivity

If the mix of reactants is enlarged to increase output, then volumetric flow-rate is improved, but mixing behaviour and heat development deteriorate

Engineering Contradiction:
Improvevolumetric flow-rateVSAvoidmixing behaviour
Core Design Contradiction:
ProductivityVSManufacturing precision

Solution Approach 1:

The patent maintains mixing quality during scaling by preserving the geometric similarity of the flow channel system. The aspect ratio of the cross-section is kept constant, and the channel dimensions are scaled according to specific relationships that maintain the flow dynamics and mixing characteristics. This ensures that mixing behavior remains consistent even as the reactor is enlarged to increase volumetric flow-rate.

Inventive Principle:
Principle #35Parameter changes

3Productivity

If the number of reactors is increased for parallelization, then volumetric flow-rate is improved, but control complexity and cleaning work increase

Engineering Contradiction:
Improvevolumetric flow-rateVSAvoidcontrol complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent merges multiple reactor functions into a single scaled-up reactor by extending the flow channel system while maintaining geometric similarity. Instead of operating multiple separate reactors in parallel that would require independent control and cleaning, the invention combines their capacity into one reactor with proportionally scaled dimensions, thereby achieving the same increased productivity with reduced operational complexity.

Inventive Principle:
Principle #5Merging (Combining)

4Productivity

If the reactor geometry is changed to increase flow-rate, then productivity is improved, but reaction conditions change

Engineering Contradiction:
Improvevolumetric flow-rateVSAvoidreaction conditions
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent employs controlled parameter changes with mathematical relationships to scale the reactor geometry. The cross-sectional area is increased by a factor k, the channel length is increased by factor k, and the aspect ratio is maintained constant. These coordinated parameter changes allow the volumetric flow-rate to increase while preserving the fluid dynamics and reaction conditions through geometric similarity.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach allows for efficient scaling of micro-reactors to achieve desired volumetric flow-rates with improved mixing efficacy and energy transfer, reducing the need for parallelization and minimizing changes in reactor geometry, thus maintaining reaction conditions and productivity.

Implementation Method 1

the smallest hydraulic diameter dh2 of the target reactor is calculated based on the relationship dh2 = dh1 * (f2/f1)^(3-n)/(7-n)

Methodology Applied
Scientific EffectHydraulic diameter relationship:

Data Source

PatentUS9023296B2Method of manufacturing a reactor and set of reactors
Publication Date: 2015.05.05 LONZA AG
  • US9023296B2 patent drawing
  • US9023296B2 patent drawing
  • US9023296B2 patent drawing

AI summary

A method of manufacturing a target reactor having a flow-channel system in which a plurality of reactants continuously flowing into said target reactor are mixed and interconvert to form a target volumetric flow-rate (f2) of a product continuously flowing out of said target reactor, wherein the smallest hydraulic diameter (dh2) of said target reactor is calculated based on the relationshipdh⁢⁢2=dh⁢⁢1⁡(f2f1)3-n7-nin a turbulent or transitional turbulent flow, wherein n is a non-integer number with 1>n≧0, between the corresponding smallest hydraulic diameter (dh1) of a standard reactor having the same fluidic type of flow-channel system, f1 is a standard volumetric flow-rate of said standard reactor carrying out the same interconversion, and f2 is said target volumetric flow-rate.