Microalgae-Clay Formula for Inflamed Mucosal Tissue Renewal

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Solution Overview

Problem

Current oral and gastrointestinal care practices fail to focus on tissue renewal and maintenance of self-regenerating biological ecosystems, leading to chronic inflammation and dysbiosis, and often use chemicals that disrupt cellular functions and perpetuate disease processes.

Innovation Solution

A microalgae-based biologically friendly base formula, combined with complementary ingredients like clay, is used to support immune regulation, microbial balance, and stem cell proliferation to accelerate tissue regeneration and restore mucosal health.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional oral and gastrointestinal care practices are used, then pathogen control is achieved, but tissue renewal and maintenance of self-regenerating biological ecosystems are neglected, leading to chronic inflammation and dysbiosis

Engineering Contradiction:
Improvetissue renewal capabilityVSAvoidchronic inflammation and dysbiosis
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent employs stem cells that naturally reside in the oral and gastrointestinal mucosa to perform self-renewal and tissue repair functions. These endogenous stem cells are activated to proliferate and differentiate, enabling the tissue to repair itself without external intervention, thus restoring the self-regenerating capability of the biological ecosystem.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent utilizes growth factors and cytokines to alter the biological parameters of the tissue environment, creating optimal conditions for stem cell activation, proliferation, and differentiation. This changes the physiological state of the tissue from a damaged, inflamed state to a regenerative, healing state.

Inventive Principle:
Principle #35Parameter changes

2Productivity

If chemicals are used in oral and gastrointestinal care, then pathogen elimination is improved, but cellular functions are disrupted and disease processes are perpetuated

Engineering Contradiction:
Improvepathogen elimination efficiencyVSAvoidcellular function disruption
Core Design Contradiction:
ProductivityVSObject-generated harmful factors

Solution Approach 1:

The patent converts the harmful effect of chronic inflammation into a beneficial healing process by utilizing the body's own inflammatory response mechanisms. Growth factors and cytokines are employed to redirect the inflammatory response from a damaging, chronic process to a controlled, regenerative process that promotes tissue repair and restores biological balance.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Solution Approach 2:

The patent introduces growth factors and cytokines as intermediary substances that mediate between the damaged tissue and the stem cells. These intermediaries signal and coordinate the complex biological processes of tissue repair, facilitating communication between different cellular components and orchestrating the regenerative response without the need for harsh chemicals.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Productivity

If stem cell proliferation is activated, then tissue repair speed is increased, but resource consumption and metabolic demand increase

Engineering Contradiction:
Improvetissue repair speedVSAvoidmetabolic demand for stem cell proliferation
Core Design Contradiction:
ProductivityVSUse of energy by moving object

Solution Approach 1:

The patent prepares the tissue environment in advance by introducing growth factors and cytokines that pre-condition the microenvironment for stem cell activation. This preliminary action ensures that when stem cells are activated, they immediately encounter optimal conditions for proliferation and differentiation, reducing the metabolic burden and accelerating the overall repair process.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent employs a feedback mechanism where growth factors and cytokines regulate stem cell proliferation based on the actual state of tissue damage. As tissue repair progresses and the microenvironment improves, the signal for stem cell activation is reduced, preventing excessive proliferation and optimizing resource utilization throughout the healing process.

Inventive Principle:
Principle #23Feedback

Data Source

PatentUS20250325609A1Method for Tissue Renewal Using A Microalgae-based Biologically Friendly Base Formula To Reverse Disease Progression And Foster Tissue Regeneration In Conditions Of Mucosal Injury And Inflammation In the Mouth And Gastrointestinal Tract
Publication Date: 2025.10.23 OM BIOME INC
  • US20250325609A1 patent drawing
  • US20250325609A1 patent drawing
  • US20250325609A1 patent drawing

AI summary

Provided is a composition comprising microalgae and clay, formulated for ingestion, application to skin, an oral cavity, or administration rectally to a mammal. Also provided is a method of treating a mammal. The method comprises administering the above composition to the mammal.