3D Microbe Distribution Test Specimen Design

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Existing test methods for microbial barrier properties of sterile products do not provide adequate information on microbe distribution in three-dimensional space, leading to partial testing and potential weak points being overlooked during transportation under changing conditions.

Innovation Solution

A test specimen with multiple measuring surfaces, each equipped with microbe collecting elements such as through-holes or vessels, allows for the determination of microbe distribution in three-dimensional space, using microbe detecting elements like nutrient-coated plates or dishes to collect and cultivate microbes, ensuring comprehensive testing of products for microbial barrier properties.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Loss of information

If traditional test methods are used to test microbial barrier properties, then the testing process is simple, but the information about microbe distribution in three-dimensional space is insufficient

Engineering Contradiction:
Improveinformation about microbe distributionVSAvoidtest specimen structure
Core Design Contradiction:
Loss of informationVSDevice complexity

Solution Approach 1:

The test specimen is divided into multiple measuring surfaces (first, second, third, fourth measuring surfaces) with microbe collecting elements distributed across each surface. This segmentation allows comprehensive collection of microbes from different spatial locations and orientations, providing complete three-dimensional distribution information without requiring a single complex detection system.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention transitions from traditional single-point or surface-level microbe detection to three-dimensional spatial distribution detection. By arranging measuring surfaces and microbe collecting elements in multiple orientations and positions within the test specimen, the system captures microbe distribution across volumetric space, adding spatial dimensionality to the measurement.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Reliability

If only sedimentation-reachable locations are tested, then the testing process is simple, but weak points of the product are not tested sufficiently

Engineering Contradiction:
Improvetesting completenessVSAvoidtest specimen configuration
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The test specimen incorporates multiple measuring surfaces oriented in different directions (front, back, left, right sides) with microbe collecting elements distributed across each surface. This segmentation ensures that microbes can be collected from all sides of the product under test, not just locations accessible by sedimentation, thereby identifying weak points throughout the entire product structure.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Different measuring surfaces are positioned to face different directions and collect microbes from specific local regions. Each measuring surface with its microbe collecting elements is optimized for detecting microbes in its specific orientation and location, ensuring comprehensive coverage of all product surfaces including those previously inaccessible to sedimentation.

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables thorough monitoring and evaluation of microbe distribution on all sides of a product, ensuring that it is exposed to microorganisms uniformly, thereby improving the reliability of microbial barrier testing and identifying potential weak points.

Implementation Method 1

it is possible for example that predominantly only the locations of a product that can be reached by sedimentation are exposed to microorganisms

Methodology Applied
Scientific EffectSedimentation: Sedimentation

Data Source

PatentUS11578352B2Test specimen, test chamber, use and method
Publication Date: 2023.02.14 AESCULAP AG
  • US11578352B2 patent drawing
  • US11578352B2 patent drawing
  • US11578352B2 patent drawing

AI summary

A test specimen for detecting or determining a spatial distribution of microbes, the test specimen having measuring surfaces and a plurality of microbe collecting elements on each of the measuring surfaces. The invention also relates to a test chamber with such a test specimen, to an associated use and to an associated method.