Microbial Biocontrol Composition for Bacterial Wilt and Aphids

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Solution Overview

Problem

Current methods for controlling bacterial wilt and other plant diseases and insects are limited by antibiotic resistance, environmental impact, and imbalanced soil microbiota, necessitating the development of environmentally friendly microbial agents.

Innovation Solution

A composition comprising Brevibacterium frigoritolerans HRS1, Bacillus niacini HRS2, Solibacillus silvestris HRS3, and Bacillus luciferensis HRS4 strains, or their spores, culture solutions, and extracts, applied to soil, roots, seeds, or plants to enhance plant immunity and control pathogens like Ralstonia solanacearum and insects like aphids.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If chemical pesticides and antibiotics are used to control plant diseases, then disease control effectiveness is improved, but antibiotic resistance develops and environmental harm increases

Engineering Contradiction:
Improvedisease control effectivenessVSAvoidantibiotic resistance and environmental harm
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the active ingredient from chemical substances to biological substances (bacterial strains). Specifically, it uses Brevibacillus laterosporus KCCM 10628P and Paenibacillus polymyxa KCCM 10629P strains that produce antibiotics naturally, thereby maintaining disease control effectiveness while avoiding the problems of chemical pesticide resistance and environmental harm

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates a composite microbial preparation by combining two different bacterial strains (Brevibacillus laterosporus and Paenibacillus polymyxa) that have complementary functions. This composite formulation enhances disease control effectiveness while maintaining environmental safety, as both strains work synergistically to suppress plant pathogens through natural mechanisms

Inventive Principle:
Principle #40Composite materials

2Object-affected harmful factors

If microbial bio-pesticides are used to control plant diseases, then environmental friendliness is improved, but they cannot cope with all species of target pathogens

Engineering Contradiction:
Improveenvironmental friendlinessVSAvoidspectrum of pathogen control
Core Design Contradiction:
Object-affected harmful factorsVSAdaptability or versatility

Solution Approach 1:

The patent achieves multi-functionality by combining two bacterial strains with different mechanisms of action. Brevibacillus laterosporus produces antibiotics effective against fungal pathogens, while Paenibacillus polymyxa produces polymyxin effective against bacterial pathogens. This combination allows a single preparation to control multiple types of plant diseases caused by different pathogen species

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent merges two distinct microbial agents into one composite preparation. By combining Brevibacillus laterosporus and Paenibacillus polymyxa in a single formulation, the patent creates a versatile bio-pesticide that can address both fungal and bacterial plant diseases, thereby expanding the spectrum of control while maintaining environmental friendliness

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The strains effectively suppress bacterial wilt in tomatoes and aphids on peppers, maintaining long-term resistance and increasing crop yields through induced systemic resistance and balanced microbial communities.

Implementation Method 1

The strains effectively suppress bacterial wilt in tomatoes and aphids on peppers, maintaining long-term resistance and increasing crop yields through induced systemic resistance and balanced microbial communities

Methodology Applied
Scientific EffectInduced systemic resistance:

Data Source

PatentUS12575574B2Composition for controlling plant disease and insect and method for preparing same
Publication Date: 2026.03.17 KOREA RES INST OF BIOSCIENCE & BIOTECHNOLOGY
  • US12575574B2 patent drawing
  • US12575574B2 patent drawing
  • US12575574B2 patent drawing

AI summary

The present invention relates to four types of Gram-positive bacteria (Brevibacterium frigoritolerans (HRS1, KCTC 14301BP), Bacillus niacini (HRS2, KCTC 14302BP), Solibacillus silvestris (HRS3, KCTC 14303BP), and Bacillus luciferensis (HRS4, KCTC 14304BP) strains), which increase resistance of plants against plant pathogens and to a composition of a biocontrol agent by using same and, more specifically, to a microbial fertilizer having a control effect against microbial diseases such as bacterial wilt occurring in crops (tomatoes, peppers, etc.), and against pests such as aphids by using the strains alone or a mixture thereof.