Microbial Biosurfactant Compositions for Safer Nematode Control

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Conventional chemical pesticides and nematicides are harmful to the environment, difficult to produce and apply effectively, and lack alternatives to methyl bromide, leading to significant crop damage and regulatory challenges.

Innovation Solution

Development of microbe-based nematicidal compositions using microbial growth by-products such as mannosylerythritol lipids (MEL) and sophorolipids (SLP) produced through cultivation processes, applied directly to nematodes or their environment, enhancing efficacy and environmental safety.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional chemical nematicides are used to control nematodes, then nematode damage is reduced, but environmental pollution and toxicity to non-target organisms increase

Engineering Contradiction:
Improvenematode control efficacyVSAvoidenvironmental pollution and toxicity
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent employs naturally occurring microorganisms and their metabolic by-products (such as organic acids, enzymes, and cell wall components) that are inherently present in soil ecosystems. These native biological agents convert potential harm from chemical pesticides into beneficial control mechanisms that suppress nematodes while maintaining environmental safety and non-target organism health.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Solution Approach 2:

The patent introduces intermediary biological agents (microorganisms and their metabolites) that mediate between the plant protection need and environmental safety. These intermediaries include biocontrol agents that indirectly control nematodes through competition, parasitism, or induction of plant resistance, rather than direct toxic contact.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If methyl bromide is used for field sterilization, then nematode, disease, and weed control is effective, but ozone layer depletion occurs

Engineering Contradiction:
Improvefield sterilization efficacyVSAvoidozone layer depletion
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent extracts and utilizes specific functional components from natural microorganisms (such as extracellular polymeric substances, organic acids, and antimicrobial metabolites) that provide sterilization and nematode control functions. This extraction replaces the need for synthetic methyl bromide while retaining the beneficial biological control mechanisms.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent changes the fundamental parameter of control agents from synthetic chemical compounds to biologically derived substances. This parameter change transforms the control mechanism from toxic chemical action to biological interaction, eliminating ozone-depleting effects while maintaining field sterilization efficacy through microbial activity and metabolite production.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If microbial biosurfactants are produced through cultivation, then production cost and complexity increase, but nematode control efficacy and environmental safety improve

Engineering Contradiction:
Improvenematode control efficacy and environmental safetyVSAvoidproduction and application complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent employs microorganisms that produce their own nematicidal metabolites and biosurfactants as part of their natural metabolic processes during cultivation. The system is designed to leverage the self-service capability of microorganisms to generate protective substances without requiring complex external intervention or processing infrastructure.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent utilizes microorganisms that perform multiple functions simultaneously: they serve as the control agent themselves, produce nematicidal metabolites, generate biosurfactants for enhanced delivery, and can be applied through various methods (soil drench, seed treatment, foliar spray). This multi-functionality reduces overall system complexity despite the biological production process.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Data Source

PatentEP3531835B1Materials and methods for the control of nematodes
Publication Date: 2026.01.07 LOCUS AGRICULTURE IP CO LLC
  • EP3531835B1 patent drawingFigure 1
  • EP3531835B1 patent drawingFigure 2
  • EP3531835B1 patent drawingFigure 3

AI summary

The invention provides materials and method for controlling pests, in particular, nematodes. The invention also provides compositions comprising biosurfactants as pesticides.