Aquaculture Feed Lipid Source Replacement with Microbial EPA DHA

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Solution Overview

Problem

The aquaculture industry faces a crisis due to the finite supply of fish oil, which is the primary source of essential fatty acids like omega-3 and omega-6 PUFAs in fish feeds, making it unsustainable to meet the growing demand for fish products while maintaining human health benefits.

Innovation Solution

Replacing fish oil in aquaculture feeds with a microbial source of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) produced using native microbes of Schizochytrium species or genetically engineered microorganisms, such as those from the order Thraustochytriales, to provide a sustainable alternative.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If fish oil is used as the primary lipid source in aquaculture feeds, then essential fatty acids (EPA and DHA) are readily supplied for fish growth and health, but the finite supply of marine pelagic fish makes this unsustainable for meeting growing global demand

Engineering Contradiction:
Improvesupply of essential fatty acidsVSAvoidsustainability
Core Design Contradiction:
Quantity of substanceVSAdaptability or versatility

Solution Approach 1:

The patent introduces plant-based omega-3 fatty acids (ALA from flaxseed oil) as an intermediary substance that can be converted by fish into EPA and DHA. This mediator approach allows the system to bypass the finite fish oil supply while still achieving the desired essential fatty acid levels in farmed fish, making the system sustainable.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent changes the source parameter of fatty acids from marine animal origin (fish oil) to plant origin (flaxseed oil). This parameter change transforms the system from dependent on finite marine resources to using renewable plant resources, thereby resolving the sustainability contradiction while maintaining essential fatty acid supply.

Inventive Principle:
Principle #35Parameter changes

2Adaptability or versatility

If fish oil is replaced with plant-based omega-3 sources, then sustainability is improved, but the EPA:DHA ratio and overall fatty acid profile may not meet fish nutritional requirements

Engineering Contradiction:
ImprovesustainabilityVSAvoidfatty acid composition
Core Design Contradiction:
Adaptability or versatilityVSManufacturing precision

Solution Approach 1:

The patent creates a composite feed formulation combining multiple lipid sources: flaxseed oil (plant-based omega-3), fish oil (marine omega-3), and vegetable oils. This composite approach allows precise control over the EPA:DHA ratio and overall fatty acid profile, meeting fish nutritional requirements while incorporating sustainable plant-based ingredients.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent uses partial replacement of fish oil with plant-based omega-3 sources rather than complete substitution. By applying partial action (replacing only a portion of fish oil), the system maintains adequate EPA:DHA ratios and fatty acid profiles while still achieving sustainability improvements.

Inventive Principle:
Principle #16Partial or excessive action

3Ease of operation

If the proportion of omega-6 to omega-3 fatty acids is increased to match terrestrial mammal diets, then dietary requirements are met, but the natural balance required for optimal fish health and growth is disrupted

Engineering Contradiction:
Improvedietary requirement fulfillmentVSAvoidfish health and growth
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The patent applies local quality by recognizing that different species have different fatty acid requirements. Instead of applying a universal mammal-based omega-6:omega-3 ratio, the system tailors the fatty acid composition to the specific nutritional needs of each fish species, maintaining optimal health and growth while meeting dietary requirements.

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach allows for the sustainable production of aquaculture meat products with a balanced EPA:DHA ratio, reducing the reliance on wild fish and ensuring the health benefits of farmed seafood, while being ecologically sound and scalable to meet global demand.

Implementation Method 1

microbial source of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) produced using native microbes of Schizochytrium species or genetically engineered microorganisms

Methodology Applied
Scientific EffectFermentation: Fermentation

Data Source

PatentUS11930832B2Feed supplement material for use in aquaculture feed
Publication Date: 2024.03.19 DSM IP ASSETS BV
  • US11930832B2 patent drawing
  • US11930832B2 patent drawing

AI summary

The invention concerns a method of sustainably producing an aquaculture meat product by feeding a fish over its dietary cycles an aquaculture feed composition, said method comprising the step of formulating an aquaculture feed composition by replacing all or part of fish oil in the composition with a single microbial source of eicosapentaenoic acid (“EPA”) and docosahex-aenoic acid (“DHA”). In a preferred embodiment, the microbial source comprising DHA and EPA derives from a microorganism/microbe of the genus Schizochytrium or Thraustochytrium.