Microbial Hemoprotein Extract for Gut Health and Weight Control

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Solution Overview

Problem

Current solutions fail to effectively improve gut health and manage obesity using microbial hemeprotein extracts, which are derived from microorganisms with high hemeprotein content.

Innovation Solution

A composition comprising a microbial hemeprotein extract obtained by culturing microorganisms with high hemeprotein content, which is used to improve intestinal flora and alleviate obesity-related conditions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If animal hemoprotein is supplied to increase lactic acid bacteria survival, then probiotic activity is improved, but weight management effectiveness deteriorates

Engineering Contradiction:
Improveprobiotic activityVSAvoidweight gain
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent uses microbial hemoprotein as an intermediary substance that indirectly supports lactic acid bacteria survival without requiring direct animal hemoprotein intake. The microbial hemoprotein serves as a safe alternative that achieves the same probiotic effect without the harmful association with animal products for weight management

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent employs hemoprotein produced by microorganisms (such as yeast) as a temporary, easily replaceable source of heme iron. This microbial hemoprotein can be produced sustainably and discarded metabolized by the body, unlike animal hemoprotein which is associated with long-term weight management issues

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

2Reliability

If lactic acid bacteria are used for probiotic effects, then intestinal flora improvement is achieved, but oxygen vulnerability limits their effectiveness

Engineering Contradiction:
Improveprobiotic activityVSAvoidoxygen resistance
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent introduces microbial hemoprotein as an intermediary that mediates between oxygen and lactic acid bacteria. The hemoprotein acts as an oxygen carrier and regulator, providing controlled oxygen availability that protects oxygen-sensitive lactic acid bacteria while maintaining their probiotic functions

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent changes the oxygen parameter in the intestinal environment by introducing microbial hemoprotein that can bind and release oxygen. This parameter change creates an optimized oxygen tension that allows lactic acid bacteria to thrive and perform their probiotic functions effectively

Inventive Principle:
Principle #35Parameter changes

3Reliability

If microbial hemoprotein extract is used to improve intestinal function, then probiotic activity increases, but the mechanism for obesity alleviation is not fully understood

Engineering Contradiction:
Improveprobiotic activityVSAvoidmechanism understanding
Core Design Contradiction:
ReliabilityVSLoss of information

Solution Approach 1:

The patent establishes a feedback mechanism where microbial hemoprotein supplementation leads to increased lactic acid bacteria survival, which in turn produces metabolites that further enhance hemoprotein utilization and provide weight management benefits. This feedback loop creates a self-reinforcing system that addresses both probiotic activity and obesity simultaneously

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The microbial hemeprotein extract enhances probiotic activity, improves gut health, and supports weight control by increasing the proportion of beneficial bacteria in the intestinal flora, thereby effectively addressing obesity.

Implementation Method 1

the supply of hemoprotein including heme iron from the outside may increase the survival of lactic acid bacteria and may serve as probiotics in the intestinal environment

Methodology Applied
Scientific EffectProbiotic activity: Fermentation

Data Source

PatentUS20250018013A1Composition including microbial hemoprotein extract for improving intestinal function and obesity
Publication Date: 2025.01.16 HEMOLAB LTD CO
  • US20250018013A1 patent drawing
  • US20250018013A1 patent drawing
  • US20250018013A1 patent drawing

AI summary

The present disclosure relates to use of microorganisms with high hemoprotein content, or culture thereof for gut health and weight control, and particularly to a composition for activating and improving intestinal flora and controlling body weight, comprising a microbial hemoprotein extract obtained from culture of microorganisms with a high hemoprotein content.