Microbicidal Composition Broadening pH Range with MIT
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Solution Overview
Problem
Existing microbicidal compositions, such as those containing 2-methyl-3-isothiazolone (MIT), are limited in their pH range application, restricting their use in various environments.
Innovation Solution
A microbicidal composition combining 2-methyl-3-isothiazolone with active compounds like those having activated methylol groups, quats, carbamates, organic acids, and aromatic alcohols, which together provide a broad antimicrobial spectrum and are effective across a wide pH range, including from 4 to 10, allowing for synergistic effects and enhanced activity.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If 2-methyl-3-isothiazolone (MIT) is combined with benzoic acid as described in European patent 1 332 675, then microbicidal activity is achieved, but the application is restricted to a limited pH range
Solution Approach 1:
The patent replaces the pH-limited benzoic acid with a group of active compounds (compounds with activated methylol groups, quats or polyquats, carbamates, organic acids, or aromatic alcohols) that can function effectively across a broad pH range of 4 to 10, making the microbicidal composition universally applicable to diverse environments including domestic cleaners, cosmetic products, and industrial formulations
Solution Approach 2:
The patent changes the chemical parameters of the second active compound from benzoic acid to compounds with different functional groups (methylol groups, quats, carbamates, organic acids, aromatic alcohols) that exhibit stable microbicidal activity across varying pH conditions, thereby expanding the operational pH window from a limited range to pH 4-10
2Device complexity
If a single active compound is used in microbicidal composition, then the formulation is simple, but the antimicrobial spectrum is narrow
Solution Approach 1:
The patent combines MIT with a second active compound from specified groups to create a synergistic mixture that broadens the antimicrobial spectrum while maintaining formulation simplicity. The combination attacks harmful organisms through multiple mechanisms, covering bacteria, yeasts, and moulds across various pH conditions without significantly complicating the formulation
Data Source
AI summary
The invention relates to a microbicidal composition which comprises a mixture of at least two components, the first component being 2-methyl-3-isothiazolone (MIT) and the second component being at least one active compound selected from the following groups of active compounds: a) compound having activated methylol groups b) quats or polyquats c) carbamates d) organic acids e) aromatic alcohols.