Synergistic Microbicidal Composition Surfactant Oxazolidine
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Solution Overview
Problem
Current microbicidal compositions lack synergistic activity against various microorganism strains, requiring higher levels of individual microbicides, which is economically and environmentally undesirable.
Innovation Solution
A synergistic microbicidal composition comprising a nonionic surfactant and cis-1-(3-chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride, 4,4-dimethyloxazolidine, or tris(hydroxymethyl)nitromethane, with specific weight ratios that provide effective microorganism control at lower microbicide levels.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If higher levels of individual microbicides are used, then effective control of microorganisms is achieved, but economic and environmental costs increase
Solution Approach 1:
The patent combines a quaternary ammonium compound (CTAC) with a nonionic surfactant (specifically IGEPAL CO-520 or TERGITOL L61) to create a synergistic microbicidal composition. This combination achieves enhanced microbial control effectiveness while reducing the required concentration of individual microbicides, thereby resolving the contradiction between reliability and quantity of substance.
Solution Approach 2:
The invention creates a composite microbicidal system by formulating specific weight ratios of CTAC (0.01-5% w/w) with nonionic surfactants (0.1-10% w/w). This composite approach leverages the complementary properties of both components to achieve superior microorganism control at lower overall concentrations, addressing both economic and environmental concerns.
2Reliability
If combinations of microbicides with synergistic activity are developed, then effective control is achieved at lower levels, but formulation complexity increases
Solution Approach 1:
The patent optimizes specific parameters including the weight ratio of CTAC to nonionic surfactant (0.01:1 to 5:1), the molecular structure of the nonionic surfactant (ethylene oxide-propylene oxide block copolymers with specific HLB values), and concentration ranges. These parameter optimizations enable synergistic activity while maintaining relatively simple formulation procedures.
Data Source
AI summary
A synergistic microbicidal composition having two components. The first component is a nonionic surfactant with structure: R1O(CH2CH(CH3)O)5(CH2CH2O)9H, where R1 is a C8 alkyl group. The second component is 4,4-dimethyloxazolidine. The weight ratio of the nonionic surfactant to 4,4-dimethyloxazolidine is from 1:0.0286 to 1:0.1143 or 1:0.32 to 1:0.9143.