Microbiome Optimization via Acidic pH and Isotonic Formulation
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current genital care products often harm genital tissues and disrupt the beneficial microbiome, leading to conditions like bacterial vaginosis, sexually transmitted diseases, and reproductive issues due to inappropriate pH levels and ingredients.
Innovation Solution
Development of isotonic, genital microbiome-friendly compositions with acidic pH, containing prebiotic oligosaccharides, metal co-factors, and borneol, along with a penile pH tracking system to optimize the genital microbiota and reduce disease incidence.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If existing cleaning products and genital therapies are used, then cleaning and therapeutic effects are achieved, but genital tissues are harmed and beneficial bacteria are killed
Solution Approach 1:
The patent changes the pH parameter of the composition from alkaline (harmful) to acidic (physiologically compatible, pH 3.8-6.5), and adjusts osmolality to be isotonic (280-320 mOsm/kg) to match natural genital fluids. This resolves the contradiction by maintaining cleaning efficacy while eliminating tissue damage and bacterial killing through proper parameter selection.
Solution Approach 2:
The patent converts potentially harmful ingredients into beneficial ones by selecting components that support the natural acidic environment of genital tissues. The composition includes prebiotics and probiotics that benefit beneficial bacteria rather than killing them, while still providing cleaning and therapeutic effects.
2Reliability
If products with inappropriate pH levels are used, then cleaning effectiveness is maintained, but microbiome balance is disrupted leading to diseases
Solution Approach 1:
The patent specifically formulates the composition with pH 3.8-6.5 to match the natural acidic environment of genital tissues, preventing microbiome disruption. This pH range maintains cleaning effectiveness while supporting beneficial bacterial growth and preventing pathogenic overgrowth, thereby eliminating the contradiction between cleaning power and microbiome safety.
Solution Approach 2:
The composition includes prebiotics and probiotics that enable the genital microbiome to maintain its own balance and defend against pathogens. The acidic pH and isotonic formulation work synergistically with natural physiological mechanisms to preserve microbiome health while providing cleaning effects.
3Loss of time
If measurement driven application regimens are used, then treatment timing is determined, but measurement precision is insufficient due to lighting and eyesight dependencies
Solution Approach 1:
The patent replaces the mechanical/visual measurement system (nitrazine paper requiring lighting and eyesight) with a chemical/spectrophotometric system using a smartphone camera and application. The smartphone's camera sensor and processing capabilities provide objective, precise pH measurement independent of lighting conditions and user eyesight, resolving the measurement precision problem while maintaining treatment timing determination.
Data Source
AI summary
The present disclosure provides compositions and methods for acidic compositions for use in optimizing the genital microbiome of a user or sexual partners of that user. The compositions may comprise a prebiotic oligosaccharide, a metal co-factor, and an essential oil comprising bornyl acetate. The compositions support the genital microbiota and are useful for, for example, hydrating, lubricating, cleaning, and/or decreasing irritation or inflammation of the urogenital and/or anogenital region of a subject, and/or enhancing the beneficial genital microbiota of a subject. Such compositions are useful before, during, and/or after sexual and/or reproductive activity. Furthermore, the compositions may have minimal or beneficial effect on gametes.