Fat-Soluble Microcapsule Antioxidant Composition for Oxidation Stability
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Solution Overview
Problem
Existing antioxidants like ethoxyquinoline and tert-butyl hydroxytoluene are limited or prohibited in the food and feed industry due to potential hazards, and existing patents do not provide effective combinations or dosages of safer alternatives such as tocopherol and vitamin C palmitate for enhancing the stability of fat-soluble active ingredients.
Innovation Solution
A combination of tocopherol and vitamin C palmitate is used with specific weight ratios to enhance the stability of fat-soluble active ingredients, with ratios ranging from 3-7:1 to 12:100, and a process involving crosslinking to form stable microcapsules.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If traditional antioxidants (ethoxyquinoline, tert-butyl hydroxytoluene, butylated hydroxyanisole) are used to prevent oxidation of fat-soluble active ingredients, then oxidation protection is improved, but safety and regulatory compliance deteriorate due to potential hazards and limited/prohibited uses in food and feed industry
Solution Approach 1:
The patent changes the chemical parameters of the antioxidant system by replacing traditional antioxidants with tocopherol and vitamin C palmitate. This substitution maintains the oxidation protection function while improving safety profile and regulatory compliance in food and feed applications.
Solution Approach 2:
The patent employs natural antioxidants (tocopherol and vitamin C palmitate) that are safer and more readily accepted in food systems, even if they require higher concentrations or more frequent replenishment compared to synthetic alternatives. This aligns with the principle of using safer, more consumable substances.
2Object-affected harmful factors
If green safe antioxidants (tocopherol, vitamin C palmitate) are used as alternatives, then safety is improved, but antioxidant effectiveness deteriorates due to lack of proven effective combinations and dosages
Solution Approach 1:
The patent combines tocopherol and vitamin C palmitate in specific weight ratios (3-7:1) to create a synergistic antioxidant system. This combination leverages the fat-soluble nature of both antioxidants to provide enhanced and sustained protection against oxidation of fat-soluble active ingredients, overcoming the limitation of using single green antioxidants.
Solution Approach 2:
The patent creates a composite antioxidant system by formulating tocopherol and vitamin C palmitate together in optimized proportions. This composite approach integrates the strengths of both antioxidants to achieve reliable oxidation protection while maintaining safety and compliance requirements.
3Device complexity
If single antioxidants are used to simplify the formulation, then formulation complexity is reduced, but antioxidant performance deteriorates due to lack of synergistic effects
Solution Approach 1:
The patent merges two antioxidants (tocopherol and vitamin C palmitate) into a unified formulation system with optimized weight ratios. While this increases formulation complexity slightly, it delivers superior antioxidant performance through synergistic effects, particularly in protecting fat-soluble active ingredients from oxidation.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The combination of tocopherol and vitamin C palmitate effectively delays oxidation, maintaining content retention rates above 94% for fat-soluble active ingredients stored at 40°C for up to 6 weeks, providing a safe and stable antioxidant solution.
Implementation Method 1
The combination of tocopherol and vitamin C palmitate effectively delays oxidation, maintaining content retention rates above 94% for fat-soluble active ingredients stored at 40°C for up to 6 weeks
Data Source
AI summary
The present invention provides a stable fat-soluble active ingredient composition, microcapsule and process for preparation and use thereof. The fat-soluble active ingredient composition comprises tocopherol, vitamin C palmitate and a fat-soluble active ingredient; wherein the weight ratio of tocopherol to vitamin C palmitate is 2-8:1, the weight ratio of a combination of tocopherol with vitamin C palmitate to the fat-soluble active ingredient is 7-13:100. The present invention obtains a novel antioxidant composition without hidden dangers for improving the stability of the fat-soluble active ingredient by screening a combination of antioxidants and adjusting their proportion and dose.