Injectable Microcapsule Implant for Hemostasis and Adhesion Prevention
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Solution Overview
Problem
Existing surgical methods fail to effectively reduce blood loss during surgery while preventing postoperative adhesions, as current devices either obscure the operating field or do not address both issues simultaneously.
Innovation Solution
The use of a viscous substance, such as gelatin or a polymeric solution, is applied to the surgical field to retard blood ingress, which can be cooled or heated for vasoconstriction, and may contain biologic agents to inhibit adhesion formation. Balloons or cuffs can be used to apply pressure and cooling, and tools can be heated or cooled to minimize blood loss. Implants can be coated with therapeutic agents for adhesion prevention.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Loss of substance
If cooling devices are applied to reduce blood loss during surgery, then blood loss is reduced, but the operating field is obscured
Solution Approach 1:
The cooling device is divided into multiple independent cooling elements or segments that can be selectively positioned. Each segment provides localized cooling to specific bleeding areas without requiring a large continuous cooling surface, thereby maintaining operating field visibility while reducing blood loss at targeted locations.
Solution Approach 2:
The invention applies cooling locally only to areas where bleeding occurs rather than cooling the entire surgical field. This localized approach reduces blood loss at specific sites while minimizing the overall visual obstruction of the operating field, allowing surgeons to maintain visibility in non-cooled areas.
2Loss of substance
If pressure bandages are applied to reduce bleeding, then blood loss is reduced, but the surgical field is obstructed
Solution Approach 1:
The pressure application device is designed to be dynamic and adjustable, allowing the surgeon to apply pressure only where and when needed during the procedure. The device can be inflated or activated selectively at different stages of surgery, providing pressure control that reduces bleeding without permanently obstructing the surgical field.
Solution Approach 2:
The pressure application mechanism is designed to be removable or collapsible, allowing it to be temporarily deployed for hemostasis and then removed or deflated to restore full surgical field access. This extraction approach enables brief pressure application to control bleeding while maintaining overall surgical accessibility.
3Object-generated harmful factors
If barrier films are applied to prevent adhesion formation, then adhesion formation is reduced, but they do not address blood loss during surgery
Solution Approach 1:
The surgical device combines multiple functions into a single system: it provides active cooling to reduce blood loss while simultaneously applying barrier properties to prevent adhesion formation. This multi-functional device eliminates the need for separate devices for each purpose, allowing both hemostasis and adhesion prevention to be achieved during the same surgical procedure.
Solution Approach 2:
The invention merges the cooling function with the barrier film function into a single integrated device. The cooling element is combined with adhesion-preventive materials, creating a unified device that addresses both blood loss control and adhesion prevention simultaneously, rather than using separate devices for each function.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach reduces blood loss and adhesion formation by maintaining a clear surgical field, minimizing tissue trauma, and accelerating healing through targeted therapeutic delivery.
Implementation Method 1
A viscous substance, such as gelatin or a polymeric solution, is applied to the surgical field to retard blood ingress
Implementation Method 2
which can be cooled or heated for vasoconstriction
Implementation Method 3
tools can be heated or cooled to minimize blood loss
Implementation Method 4
Implants can be coated with therapeutic agents for adhesion prevention
Data Source
AI summary
The present disclosure provides a system for injecting a drug eluting construct in a patient. The construct includes multiple cellular based microcaspules, wherein the multiple cellular based microcapsules create at least one of a plurality of layers or sections of microcapsules joined together to comprise an implant. There is a medicinal agent within the microcapsules. A syringe and needle inject the implant constructed of microcapsules into the patient at least one of during and after a surgical procedure. The medicinal agent controllably releases into the patient both immediately and at a delayed time.