Microchamber Assay Imaging with Aspheric Lenses and Stray-Light Shielding
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Solution Overview
Problem
Existing digital assay devices lack convenience and accuracy in their operation.
Innovation Solution
An analysis device comprising a device holder, light source, aspheric lenses, imaging apparatus, and optical filters, with a light-shielding unit to suppress stray light and improve spatial resolution, while maintaining image flatness and reducing chromatic aberration.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If conventional lenses are used in the imaging apparatus, then the device structure is simple, but chromatic aberration occurs and spatial resolution deteriorates
Solution Approach 1:
The patent employs aspheric lenses instead of conventional spherical lenses to correct chromatic aberration and improve spatial resolution. The aspheric surfaces allow for better control of light rays across different wavelengths, eliminating the need for complex multi-element lens systems while maintaining high imaging quality.
2Measurement precision
If no light shielding is provided, then the device structure is simple, but stray light increases causing background noise
Solution Approach 1:
The patent introduces a light-shielding unit that selectively blocks stray light paths while allowing the desired optical path to remain open. This extraction approach removes only the harmful stray light components without interfering with the main imaging function, thereby improving signal-to-noise ratio with minimal added complexity.
3Measurement precision
If multiple optical components are added to improve image quality, then measurement precision improves, but device complexity increases
Solution Approach 1:
The patent combines multiple optical correction functions into a single aspheric lens element. The aspheric lens simultaneously corrects for spherical aberration, chromatic aberration, and field curvature that would otherwise require multiple separate lens elements, thereby improving image quality while minimizing the number of components.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device achieves digital assay with enhanced convenience and high accuracy by minimizing background noise and improving image quality.
Implementation Method 1
one or more aspheric lenses placed between the imaging apparatus and the device holder... while chromatic aberration is suppressed
Implementation Method 2
one or more aspheric lenses placed such that the optical axis thereof is substantially parallel to a normal line of a first surface of the microchamber device
Implementation Method 3
a first optical filter positioned between the microchamber device and the imaging apparatus, the first optical filter cutting off light emitted from the light source and allowing at least a portion of light having a longer wavelength than the wavelength of the light emitted from the light source to pass therethrough
Implementation Method 4
a light-shielding unit configured to suppress the detection, by the imaging apparatus, of light other than light generated from the microchamber device
Data Source
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AI summary
The present disclosure relates to an analysis device including: a device holder configured to hold a microchamber device; a light source configured to irradiate the microchamber device with light; one or more aspheric lenses placed such that the optical axis thereof is substantially parallel to a normal line of a first surface of the microchamber device; an imaging apparatus configured to image the microchamber device via the aspheric lenses; a first optical filter positioned between the microchamber device and the imaging apparatus, the first optical filter cutting off light emitted from the light source and allowing at least a portion of light having a longer wavelength than the wavelength of the light emitted from the light source to pass therethrough; and a light-shielding unit configured to suppress the detection, by the imaging apparatus to be held, of light other than light generated from the microchamber device and detected by the imaging apparatus to be held via the first optical filter and the aspheric lenses.