Microchip Flow Path Layout for One-Side Microparticle Sorting
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Solution Overview
Problem
Conventional microchips require separate installation of collection containers or bags on different side surfaces, complicating handling and integration with sorting devices.
Innovation Solution
A microchip design with a sample liquid inlet and sorting flow path on the same side surface, along with optional sheath and buffer liquid inlets, and a flow path connecting member, allowing easy integration and handling, and featuring optical detection regions and curvatures to enhance sorting accuracy.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If the sample liquid inlet and terminal end of the sorting flow path are formed on different side surfaces, then the microparticle sorting function is achieved, but the handling complexity increases and integration becomes difficult
Solution Approach 1:
The patent merges the sample liquid inlet and the terminal end of the sorting flow path onto the same side surface of the microchip. This consolidation allows both the input and output ports to be located on one side, enabling simplified connection to collection containers and reducing the number of sides that need to be accessed during operation, thereby improving handling ease and reducing integration complexity.
2Productivity
If collection containers are installed on different side surfaces, then the sorting function is complete, but the installation and removal process becomes time-consuming
Solution Approach 1:
By positioning both the sample liquid inlet and the terminal end of the sorting flow path on the same side surface, the patent enables both collection containers to be accessed from one side of the microchip. This eliminates the need to access opposite sides of the device, significantly reducing the time required for installing and removing collection containers while maintaining complete sorting functionality.
3Adaptability or versatility
If multiple inlets and flow paths are added, then the sorting capability is enhanced, but the structural complexity increases
Solution Approach 1:
The patent resolves structural complexity by reorganizing the spatial arrangement of multiple inlets and flow paths. By positioning all inlet ports (sample liquid inlet, sheath liquid inlet, buffer liquid inlet) and the terminal end of the sorting flow path on the same side surface, the patent creates a compact, one-sided interface design. This dimensional reorganization allows multiple functional elements to coexist without increasing overall structural complexity, as all connections can be made from a single access side.
Data Source
AI summary
To provide a microchip that is easily handled.Provided is a microchip having a plate shape and including: a sample liquid inlet into which a sample liquid is introduced; a main flow path through which the sample liquid introduced from the sample liquid inlet flows; and a sorting flow path into which a target sample is sorted from the sample liquid, in which the sample liquid inlet and a terminal end of the sorting flow path are formed on a same side surface. Furthermore, a sample sorting kit including the microchip is also provided. Moreover, a microparticle sorting device on which the microchip is mounted is also provided.