Microdialysis Flow Feedback Using Weighing-Based Leak Detection
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Solution Overview
Problem
Existing microdialysis systems lack real-time flow rate monitoring and fail to address issues such as clogging, leakage, and improper syringe positioning, while also requiring non-contact liquid collection and treatment for toxic substances.
Innovation Solution
A microdialysis system with a flow rate feedback device that includes a calibration weighing module, automatic drainage mechanism, and a display module to monitor pipeline flow status by weighing collected liquid, providing real-time feedback and automatic liquid disposal.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If no flow rate monitoring device is installed, then the system structure remains simple, but clogging and leakage issues cannot be detected in time
Solution Approach 1:
The patent implements a feedback mechanism where the weighing module continuously monitors the weight of the liquid collection container and transmits data to the control display module. The control display module compares current weight with previous weight to detect flow rate changes, enabling real-time detection of blockages or leaks in the connecting pipelines.
Solution Approach 2:
The patent replaces complex mechanical flow rate sensors with a simpler weighing-based detection system. By measuring the weight change of the liquid collection container over time, the system calculates flow rate indirectly, avoiding the need for complex mechanical or electronic flow sensors while achieving reliable flow monitoring.
2Object-affected harmful factors
If manual liquid collection is used, then the device complexity is low, but toxic dialysate requires manual handling which is unsafe
Solution Approach 1:
The patent implements an automatic drainage function where the control display module automatically controls the drainage pump to remove collected liquid from the container when it reaches a predetermined weight threshold. This eliminates manual handling of toxic dialysate while maintaining relatively simple device structure through automated control.
Solution Approach 2:
The weighing module provides continuous feedback on liquid accumulation weight to the control display module, which automatically triggers the drainage pump when the predetermined threshold is reached. This closed-loop control enables safe automatic handling of toxic substances without requiring manual intervention.
3Measurement precision
If real-time flow monitoring is implemented, then flow status can be monitored continuously, but the measurement precision requirement increases
Solution Approach 1:
The patent replaces complex electronic flow rate sensors with a weighing-based measurement system. The weighing module measures the weight of the liquid collection container at different time points, and the control display module calculates flow rate from these weight changes. This approach achieves real-time flow monitoring with relatively simple equipment while maintaining adequate measurement precision for detecting blockages and leaks.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables timely detection of pipeline issues, ensures accurate flow rate monitoring, and integrates non-contact liquid collection and treatment, enhancing the reliability and safety of microdialysis processes.
Implementation Method 1
The calibration weighing module is configured to regularly measure the weight of a liquid in the liquid collection container
Data Source
AI summary
A microdialysis system includes: an input device, first and second connecting pipelines and a flow feedback device that includes a connecting needle, a liquid collecting tank, a calibration weighing module, and a flow feedback control display module; the weighing module weighs the liquid in the liquid collecting tank regularly according to conditions and a program set in the display module and transmits a measured liquid weighing value to the display module; the display module performs a difference operation between the current liquid weighing value and the previous liquid weighing value to obtain a weighing sampling difference value, compares the weighing sampling difference value with a preset value to monitor whether the connecting needle outputs liquid normally, and further feeds back a flow state of fluid in the first and second connecting pipelines. In the microdialysis system, the flow state of each connecting pipeline is monitored by weighing the collected liquid.