Penetrating Microelectrode Array for Controlled Tissue Ablation

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Solution Overview

Problem

Existing skin rejuvenation and tissue treatment methods, such as CO2 laser systems and needle electrode approaches, face limitations in controlling channel aspect ratio and thermal damage zones, with CO2 lasers being cumbersome and costly, and needle electrodes not effectively forming empty channels for tissue tightening.

Innovation Solution

An electrosurgical electrode array that ablates tissue during insertion to form channels with adjustable aspect ratio and controlled thermal damage zones, using a combination of ablative and coagulative waveforms to create empty channels and provide deep tissue heating.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If CO2 laser systems are used for ablative fractional resurfacing, then tissue ablation and coagulation can be achieved, but the device size is large, the system is cumbersome, and the cost is high

Engineering Contradiction:
Improvetissue ablation effectivenessVSAvoiddevice size and system complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent replaces the complex mechanical laser beam delivery system with a simpler electrical system. Instead of using laser beams to ablate tissue, the invention uses electrical current delivered through needle electrodes to achieve the same ablation effect, thereby eliminating the need for large laser equipment and articulated arm beam delivery systems

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The invention extracts the essential function of tissue ablation from the complex laser system and implements it through a simpler electrical current delivery mechanism using needle electrodes, removing the cumbersome laser generation and delivery components while retaining the core therapeutic effect

Inventive Principle:
Principle #2Taking out (Extraction)

2Length of moving object

If CO2 laser systems are used for tissue drilling, then channels can be created, but the aspect ratio (depth-to-width) is limited to approximately 10

Engineering Contradiction:
Improvechannel depthVSAvoidaspect ratio control
Core Design Contradiction:
Length of moving objectVSManufacturing precision

Solution Approach 1:

The patent changes the fundamental parameter of energy delivery from optical (laser) to electrical current. This parameter change enables the creation of channels with much higher aspect ratios because electrical current can be delivered through very thin needle electrodes (25-250 micrometers diameter) to great depths, allowing aspect ratios far exceeding the laser limit of 10

Inventive Principle:
Principle #35Parameter changes

3Reliability

If CO2 laser ablation is used, then tissue channels are created, but the thermal damage zone at side walls is similar or larger than at the bottom

Engineering Contradiction:
Improvechannel formationVSAvoidthermal damage zone distribution
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent applies local quality by using insulated needle electrodes that concentrate electrical current primarily at the electrode tip rather than along the entire electrode length. This creates a localized ablation zone at the channel bottom with minimal thermal damage to the side walls, achieving the desired thermal damage distribution pattern that differs from laser ablation

Inventive Principle:
Principle #3Local quality

4Reliability

If needle electrodes are inserted for non-ablative treatment, then tissue coagulation occurs, but no empty channels are formed for effective skin tightening

Engineering Contradiction:
Improvetissue coagulationVSAvoidchannel formation quality
Core Design Contradiction:
ReliabilityVSManufacturing precision

Solution Approach 1:

The patent uses a composite approach by combining ablative and non-ablative functions in a single needle electrode system. The electrodes deliver electrical current that simultaneously coagulates tissue and creates empty channels through controlled ablation, achieving both effects that were previously mutually exclusive

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach offers flexible control over therapeutic parameters, reduces surface damage, and enhances healing by creating empty channels with a desirable coagulation pattern, providing more effective skin tightening and improved healing compared to conventional methods.

Implementation Method 1

electrode array configured to ablate tissue during insertion of the electrode array into tissue being treated

Methodology Applied
Scientific EffectAblation: Ablation

Implementation Method 2

form coagulation zone at the edges of the channels

Methodology Applied
Scientific EffectJoule heating: Joule Heating

Implementation Method 3

The epidermis and part of the dermis demonstrate columns of thermal coagulation that surround tapering ablative zones

Methodology Applied
Scientific EffectThermal coagulation: Coagulation

Implementation Method 4

deep heating of the treated tissue can be performed by applying an additional waveform to the tissue with the electrode array

Methodology Applied
Scientific EffectElectrical heating: Joule Heating

Data Source

PatentUS9254168B2Electro-thermotherapy of tissue using penetrating microelectrode array
Publication Date: 2016.02.09 MEDTRONIC ADVANCED ENERGY LLC
  • US9254168B2 patent drawing
  • US9254168B2 patent drawing
  • US9254168B2 patent drawing

AI summary

Electrosurgical therapy is provided with an electrode array configured to ablate tissue during insertion of the electrode array into tissue being treated. Once the electrode array is fully inserted, deep heating of the treated tissue can be performed by applying an additional waveform to the tissue with the electrode array. Optionally, the electrical waveform can be varied continuously during insertion of the electrode array to control the extent of coagulation at the side walls and at the bottom of the channels produced by tissue ablation.