Microencapsulated Essential Oil Blend for Cannabinoid Synergy

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Solution Overview

Problem

The cannabis confection process results in significant loss of micronutrients like terpenes, amino acids, and carbohydrates, which are essential for synergistic effects with cannabinoids, leading to delayed onset, reduced magnitude, and shorter duration of effects, along with increased unwanted side effects.

Innovation Solution

A pharmaceutical composition combining a primary essential oil and a secondary essential oil, both microencapsulated using a food-grade polysaccharide, to replenish lost micronutrients and enhance the benefits of cannabinoids by supporting the human endocannabinoid system.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If cannabis undergoes confection process (harvesting, curing, extraction, formulation, concentration), then cannabinoids are obtained, but micronutrients (terpenes, amino acids, carbohydrates) are lost

Engineering Contradiction:

Improvecannabinoid concentrationVSAvoidmicronutrient loss

Core Design Contradiction:

Quantity of substanceVSLoss of substance

Solution Approach 1:

The patent applies preliminary action by adding micronutrients back into the cannabis extract after the confection process has already occurred. Rather than preventing loss during processing, the invention replenishes terpenes, amino acids, and carbohydrates post-extraction to restore the entourage effect, demonstrating a corrective approach to already-processed material

Inventive Principle:

Principle #10Preliminary action

Solution Approach 2:

The patent recovers lost micronutrients by intentionally adding them back to the cannabis extract. This principle is applied by taking substances that were discarded or lost during conventional processing and reintroducing them in controlled amounts to restore the original synergistic profile of cannabis

Inventive Principle:

Principle #34Discarding and recovering

2Productivity

If micronutrients are lost during processing, then cannabinoid extract is obtained, but onset time increases

Engineering Contradiction:

Improveextract production efficiencyVSAvoidonset time delay

Core Design Contradiction:

ProductivityVSLoss of time

Solution Approach 1:

The patent applies preliminary action by pre-formulating micronutrient blends that are added to the extract before administration. This pre-preparation of complementary substances ensures rapid availability of synergistic compounds when the product is consumed, thereby reducing onset time despite efficient processing

Inventive Principle:

Principle #10Preliminary action

3Productivity

If micronutrients are lost during processing, then cannabinoid extract is obtained, but duration of effects decreases

Engineering Contradiction:

Improveprocessing efficiencyVSAvoidduration of effects

Core Design Contradiction:

ProductivityVSDuration of action of moving object

Solution Approach 1:

The patent recovers lost micronutrients by adding them back to the extract in controlled amounts. This recovery of terpenes, amino acids, and carbohydrates extends the duration of effects by maintaining the entourage effect, allowing the cannabinoids to remain active and effective for longer periods

Inventive Principle:

Principle #34Discarding and recovering

4Productivity

If micronutrients are lost during processing, then cannabinoid extract is obtained, but unwanted side effects increase

Engineering Contradiction:

Improveextract production efficiencyVSAvoidunwanted side effects

Core Design Contradiction:

ProductivityVSObject-generated harmful factors

Solution Approach 1:

The patent applies homogeneity by creating a balanced formulation where micronutrients are added in specific ratios that mirror the natural cannabis profile. This homogeneous distribution of cannabinoids and micronutrients ensures consistent effects and reduces unwanted side effects by maintaining the natural synergistic relationships found in whole cannabis

Inventive Principle:

Principle #33Homogeneity

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition provides a faster onset, increased magnitude, and longer duration of effects, while reducing side effects, by delivering essential micronutrients effectively to the bloodstream, replicating the original cannabis profile and supporting the endocannabinoid system.

Implementation Method 1

The liquid form of the primary essential oil and the secondary essential oil are respectively transformed into a powder form by performing a microencapsulation process

Methodology Applied

Scientific EffectMicroencapsulation:

Data Source

PatentUS20210330596A1Pharmaceutical composition for use in a combination with cannabinoids to enhance benefits of cannabinoids to support human endocannabinoid system

Publication Date: 2021.10.28 MENDOZA MONTOYA JORGE A

AI summary

The embodiments herein provide a pharmaceutical composition for use in a combination with cannabinoids that includes a primary essential oil, and a secondary essential oil to support the human endocannabinoid system. The primary essential oil replenishes a plurality of first micronutrients lost during the processing of cannabis. The primary essential oil contains a first therapeutically effective amount of crude cannabis essential oil. The secondary essential oil replenishes a plurality of second micronutrients lost during the processing of cannabis. The secondary essential oil contains a second therapeutically effective amount of crude cannabis essential oil. The primary essential oil and the secondary essential oil are in a liquid form. The liquid form of the primary essential oil and the secondary essential oil are respectively transformed into a powder form by performing a microencapsulation process.