Microengineered Multipole Ion Guide Alignment

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Solution Overview

Problem

Conventional multipole ion guides face challenges in secure and accurate mounting with independent electrical connections, especially as the field radius decreases or the number of rods increases, affecting ion confinement and transmission efficiency in mass spectrometer systems.

Innovation Solution

A microengineered multipole rod assembly is fabricated using microengineering principles, with rods mounted on precision substrates and connected via conductive tracks, allowing for accurate alignment and electrical isolation, enabling the use of hexapole and octupole configurations that require reduced rf amplitudes and can operate at higher pressures.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If conventional machining techniques are used to construct multipole ion guides with drilled and tapped rods held against ceramic supports, then the mounting arrangement can be securely assembled, but the alignment accuracy and electrical connection reliability deteriorate as the field radius decreases and the number of rods increases

Engineering Contradiction:
Improvealignment accuracyVSAvoidmounting arrangement complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent replaces conventional mechanical machining techniques with microfabrication processes. The rods are precisely positioned using microengineered mounting structures fabricated through semiconductor-style processes, eliminating the need for drilled and tapped holes and retaining screws. This substitution enables accurate alignment and reliable electrical connections even as the field radius decreases and rod count increases.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Volume of moving object

If the field radius is decreased to reduce the size of mass spectrometer components, then the overall system size is reduced, but the ability to provide secure mounting and accurate alignment with independent electrical connections deteriorates

Engineering Contradiction:
Improveion guide sizeVSAvoidmounting accuracy
Core Design Contradiction:
Volume of moving objectVSManufacturing precision

Solution Approach 1:

The patent segments the ion guide into modular components - individual rods mounted on separate microfabricated supports with independent electrical connections. Each rod can be precisely positioned and electrically connected independently, allowing the overall structure to be miniaturized while maintaining manufacturing precision. The segmented approach enables scalable configurations (quadrupole, hexapole, octupole) without compromising alignment accuracy.

Inventive Principle:
Principle #1Segmentation

3Reliability

If conventional wire loop electrical connections are used straddling alternate rods, then electrical connections can be made between rods, but the reliability of independent electrical connections deteriorates as the number of rods increases and field radius decreases

Engineering Contradiction:
Improveelectrical connection reliabilityVSAvoidelectrical connection structure
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent replaces wire loop electrical connections with direct microfabricated electrical contacts. Each rod is electrically connected through integrated contact structures formed during the microfabrication process, providing reliable independent electrical connections without the mechanical complexity of wire loops. This substitution ensures consistent electrical connectivity even as the number of rods increases and the field radius decreases.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The microengineered ion guide system reduces the overall size of mass spectrometer components, increases the range of accessible pressures, and allows for smaller pumps, enhancing ion confinement and transmission efficiency while minimizing electrical discharge risks.

Implementation Method 1

a microengineered multipole rod assembly (145) comprising a plurality of rods (530) arranged circumferentially about an ion beam axis (535)... the rods collectively generating an electric field that confines the trajectories of the ions

Methodology Applied
Scientific EffectIon confinement via multipole electric field: Electric Field

Implementation Method 2

Ions created at atmospheric pressure are generally transferred to high vacuum for mass analysis using one or more stages of differential pumping. These intermediate stages are used to pump away most of the gas load.

Methodology Applied
Scientific EffectDifferential pumping: Pressure Gradient

Data Source

PatentEP2779207B1Microengineered multipole ion guide
Publication Date: 2016.05.18 MICROSAIC SYSTEMS PLC
  • EP2779207B1 patent drawingFigure 1~2
  • EP2779207B1 patent drawingFigure 3~4
  • EP2779207B1 patent drawingFigure 5~6

AI summary

A microengineered multipole rod assembly for use as an ion guide for use in miniature mass spectrometer systems is described. Exemplary methods of mounting rods in hexapole, octupole, and other multipole geometries are described. The rods forming the ion guide are supported by etched silicon structures provided on first and second substrates.