Microfluidic Chip Fluid Handling Device with Sealed Independent Tanks

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Solution Overview

Problem

Current microfluidic systems face challenges with multiple reservoirs, including space constraints, complexity in manufacturing, fluid cross-contamination, and inefficiencies in fluid handling and sample collection.

Innovation Solution

A device with multiple independent fluid tanks that can be directly plugged into a microfluidic chip, eliminating the need for external tubing and reducing dead volume, while ensuring sealed fluidic communication and efficient fluid delivery and collection.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If multiple external reservoirs are used for fluid handling, then fluid storage capacity is improved, but device complexity and space constraints worsen

Engineering Contradiction:
Improvefluid storage capacityVSAvoiddevice complexity
Core Design Contradiction:
Quantity of substanceVSDevice complexity

Solution Approach 1:

The patent merges multiple separate external reservoirs into a single integrated device body containing multiple internal fluid tanks. This integration reduces the number of separate components, simplifies the overall device structure, and eliminates the need for multiple external connections while maintaining the ability to store and deliver multiple different fluids through dedicated tanks and channels.

Inventive Principle:
Principle #5Merging (Combining)

2Ease of operation

If external tubing is used to connect reservoirs to chip, then fluid delivery is enabled, but dead volume increases and contamination risk worsens

Engineering Contradiction:
Improvefluid deliveryVSAvoiddead volume
Core Design Contradiction:
Ease of operationVSLoss of substance

Solution Approach 1:

The patent extracts and eliminates the external tubing component from the fluid delivery system. By integrating the fluid tanks directly onto the chip device and providing direct fluidic connections, the design removes the intermediate tubing that creates dead volume, thereby reducing fluid loss and contamination risk while maintaining efficient fluid delivery capability.

Inventive Principle:
Principle #2Taking out (Extraction)

3Quantity of substance

If multiple external reservoirs are used, then fluid storage is improved, but manufacturing complexity and cost worsen

Engineering Contradiction:
Improvefluid storageVSAvoidmanufacturing complexity
Core Design Contradiction:
Quantity of substanceVSEase of manufacture

Solution Approach 1:

The patent combines multiple separate reservoir manufacturing processes into a single integrated device fabrication process. By incorporating multiple fluid tanks within one device body that can be manufactured as a single unit or pre-assembled module, the design simplifies manufacturing operations, reduces assembly steps, and lowers production complexity and cost compared to producing and assembling multiple separate external reservoirs.

Inventive Principle:
Principle #5Merging (Combining)

4Ease of operation

If traditional reservoir systems are used, then fluid handling is enabled, but fluid cross-contamination and fluid loss worsen

Engineering Contradiction:
Improvefluid handlingVSAvoidcontamination risk
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The patent segments the fluid storage system into multiple independent, sealed tanks within the device body, each dedicated to storing a specific fluid. This segmentation with individual sealed containers prevents cross-contamination between different fluids while maintaining ease of operation through dedicated delivery channels for each tank, thereby improving reliability by eliminating contamination pathways present in traditional shared reservoir systems.

Inventive Principle:
Principle #1Segmentation

Data Source

PatentEP4541459A1A device for a microfluidic chip
Publication Date: 2025.04.23 LIVEDROP
  • EP4541459A1 patent drawingFigure 1
  • EP4541459A1 patent drawingFigure 2~3
  • EP4541459A1 patent drawingFigure 4

AI summary

The invention relates to a device suitable for being plugged directly into a microfluidic chip which has at least one opening, the device comprising a body which contains a plurality of independent fluid tanks, wherein each fluid tank has an inlet configured for receiving a fluid and an outlet, forming an open end of the fluid tank and being configured to deliver the corresponding fluid directly into at least one opening of the microfluidic chip, characterized in that each outlet has a smaller opening compared with its corresponding inlet and is configured to be in a sealed fluidic communication with at least one opening of the microfluidic chip.