Micro-fluidic Chip Integrated Laser Source
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Solution Overview
Problem
Existing digital micro-fluidic chips for biological detection lack integrated light sources, which hinders the miniaturization and portability of detection equipment.
Innovation Solution
A micro-fluidic chip is designed with an integrated laser source and detection element, allowing for on-chip illumination and detection of droplets, thereby eliminating the need for external light sources.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If light sources are installed on external detection apparatus, then detection function is achieved, but device size and portability are compromised
Solution Approach 1:
The patent merges the light source function into the micro-fluidic chip by integrating a laser source directly onto the chip substrate. This combines previously separate components (chip and external light source) into a single integrated unit, enabling portable detection while maintaining detection functionality through on-chip illumination for droplet analysis
2Volume of moving object
If light sources are integrated into the micro-fluidic chip, then device miniaturization and portability are improved, but device complexity increases
Solution Approach 1:
The patent uses hydrophobic layers and capillary forces to control droplet movement and positioning on the chip. The hydrophobic layer pattern creates specific wetting regions that guide droplets to designated areas where the laser source illuminates them, enabling automated droplet manipulation without complex mechanical actuators or external control systems
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The integration of a laser source and detection element within the micro-fluidic chip enhances its portability and miniaturization, while improving the accuracy and efficiency of biochemical reactions and detection processes.
Implementation Method 1
a laser source on the upper substrate side or the lower substrate side and configured to provide illumination for detection of the droplet
Implementation Method 2
a detection element on the upper substrate side or the lower substrate side and configured to detect the droplet
Implementation Method 3
a driving electrode on an upper substrate side or a lower substrate side, the driving electrode being configured to control the droplet to move in a powered-on state
Data Source
AI summary
The present disclosure provides a micro-fluidic chip, a method for fabricating the same, and a micro-fluidic device. The micro-fluidic chip includes: an upper substrate and a lower substrate assembled to form a cell with a gap between the upper substrate and the lower substrate, the gap being configured to accommodate a droplet; a driving electrode on an upper substrate side or a lower substrate side, the driving electrode being configured to control the droplet to move in a powered-on state, wherein the micro-fluidic chip further includes a laser source on the upper substrate side or the lower substrate side and configured to provide illumination for detection of the droplet.