Microfluidic Chip Temperature Detection Unit With Light-Shielding Layer
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Solution Overview
Problem
Current temperature measurement methods in microfluidic systems face challenges with accuracy due to external interference and temperature gradient errors, particularly in contact and integrated types, where non-contact methods are prone to poor detection and integrated methods suffer from low detection accuracy.
Innovation Solution
A microfluidic chip with a temperature detection unit that includes a temperature sensor integrated on the substrate, connected via lead groups to an external constant current source and voltmeter, allowing for direct contact with the liquid droplet and minimizing external interference, using a combination of wire and block temperature-sensitive resistors with adjustable resistance ratios and a light-shielding layer to enhance measurement precision.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If contact type temperature measurement is used in microfluidic systems, then the temperature sensor can directly detect the liquid droplet temperature, but external interference and temperature gradient errors reduce measurement accuracy
Solution Approach 1:
The patent introduces a light-shielding layer as an intermediary component between the temperature sensor and the external environment. This layer blocks external light interference that would otherwise affect the temperature measurement accuracy, allowing the temperature sensor to directly contact the liquid droplet while being protected from harmful external factors.
Solution Approach 2:
The patent applies local quality by creating a controlled microenvironment around the temperature sensor. The light-shielding layer is specifically positioned over the temperature sensor area to provide localized protection from external interference, while maintaining thermal contact with the liquid droplet for accurate temperature detection.
2Difficulty of detecting and measuring
If integrated temperature sensors are used in microfluidic chips, then the detection capability is improved, but temperature gradient errors and low detection accuracy persist
Solution Approach 1:
The light-shielding layer serves as a mediator that protects the integrated temperature sensor from external light interference while allowing thermal conduction. This enables the sensor to maintain direct thermal contact with the liquid droplet for accurate detection while being shielded from electromagnetic or optical interference that would reduce measurement precision.
Solution Approach 2:
The patent changes the physical parameters of the measurement environment by introducing the light-shielding layer, which modifies the thermal and optical properties in the local measurement zone. This parameter change protects the temperature sensor from external interference while maintaining the necessary thermal contact for accurate temperature detection.
3Object-affected harmful factors
If non-contact temperature measurement methods are used, then external interference is reduced, but detection accuracy becomes poor
Solution Approach 1:
The light-shielding layer acts as a protective intermediary that enables contact-type measurement to achieve the benefits of non-contact methods. By blocking external light interference, it allows the temperature sensor to directly contact the liquid droplet without suffering from the external interference problems that plague non-contact methods, thereby achieving both direct thermal contact and protection from harmful factors.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This solution improves temperature measurement accuracy by eliminating external interference and reducing temperature gradient errors, enabling precise detection of reaction temperatures critical for biochemical reactions.
Implementation Method 1
the first lead group is configured to transmit a constant current to the temperature sensor
Implementation Method 2
the temperature sensor includes a first temperature-sensitive resistor and a second temperature-sensitive resistor electrically connected
Implementation Method 3
the second lead group is configured to electrically connect the temperature sensor and an external voltmeter
Data Source
AI summary
The application provides a microfluidic chip, a temperature measurement method using the same, and an analysis device, which relates to the field of microfluidic technology. The microfluidic chip includes: a substrate and at least one microfluidic module located on the substrate, wherein the microfluidic module includes a droplet control unit and at least one temperature detection unit, and wherein the temperature detection unit includes a temperature sensor, a first lead group and a second lead group, the temperature sensor is fixed on the substrate, the first lead group and the second lead group are electrically connected with the temperature sensor respectively, the first lead group is configured to transmit a constant current to the temperature sensor, and the second lead group is configured to electrically connect the temperature sensor and an external voltmeter.