Microfluidic Device 3D Coil Magnetic Field Heat Reduction
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Solution Overview
Problem
Current microfluidic technologies face challenges in generating a flexible and adjustable magnetic field for immunoassays and instant diagnosis due to heat generation issues with planar electromagnetic coils, which can affect biochemical reactions and experimental results.
Innovation Solution
A microfluidic device with a substrate configuration that includes a first electrode and a plurality of coils connected in parallel, where the coils are arranged to generate a magnetic field, and a mixing assist structure like an ∧-shaped protrusion to facilitate fluid mixing, while minimizing heat production by using electrodes with lower resistivity materials.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Power
If planar electromagnetic coils are used to generate magnetic field, then magnetic field generation capability is improved, but heat generation increases affecting biochemical reactions
Solution Approach 1:
The patent replaces the planar electromagnetic coil system with a three-dimensional coil structure that generates magnetic field through a different geometric configuration. This substitution reduces the resistive heating effect while maintaining the magnetic field generation capability, solving the contradiction between power output and heat generation.
Solution Approach 2:
The patent transitions from a two-dimensional planar coil layout to a three-dimensional coil structure extending in the vertical dimension. This dimensional change allows for optimized current distribution and reduced resistance, thereby generating the required magnetic field with significantly reduced heat production that could otherwise affect biochemical reactions.
2Extent of automation
If multiple control assemblies are integrated on chip, then device integration and automation are improved, but device complexity increases
Solution Approach 1:
The patent combines multiple control assemblies into a single integrated chip structure, merging functions that would traditionally require separate devices. By integrating multiple coils, electrodes, and control circuits into one unified platform, the system achieves high automation while managing complexity through modular design and shared components.
Solution Approach 2:
The patent designs control assemblies with universal components that can serve multiple functions. The three-dimensional coil structure and electrode arrangements are configured to perform various magnetic field generation tasks across different control assemblies, reducing the need for specialized components and thereby managing overall device complexity while maintaining high integration.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device achieves flexible control of the magnetic field and reduces heat generation, maintaining optimal temperatures for biochemical reactions, enhancing the accuracy and efficiency of immunoassays and molecular diagnostics.
Implementation Method 1
the first electrode is configured to input currents into the plurality of coils, and the plurality of coils are connected in parallel to the second electrode
Implementation Method 2
providing an electric current to the coil through the first electrode and the second electrode to cause the magnetic particle with the detection sample bound to a surface of the magnetic particle to be attracted in a magnetic field generated by the coil
Implementation Method 3
the mixing assist structure is in the channel and configured to mixing the fluid
Data Source
AI summary
A microfluidic device, a microfluidic detection assembly and a detection method for the microfluidic device. The microfluidic device includes a first substrate and a second substrate; the first substrate and the second substrate are oppositely arranged to define a channel between the first substrate and the second substrate, the channel is configured for liquid to flow, the first substrate includes a base substrate and a plurality of control assemblies which are arranged on the base substrate along an extending direction of the channel, each of the plurality of control assemblies includes: a first electrode, a second electrode and a plurality of coils, and the first electrode is configured to input currents into the plurality of coils, and the plurality of coils are connected in parallel to the second electrode.