Microfluidic Channel Filter Nanoimprinting Fabrication

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Solution Overview

Problem

Existing microfluidic devices face challenges in integrating microfilters with controlled filter characteristics, such as particle filtration size, due to complex assembly processes and inconsistent filter performance.

Innovation Solution

A nanoimprinting fabrication method is used to directly integrate a micro/nanoporous filter into microfluidic channels, allowing for precise patterning of pore size and density, simplifying the integration process and ensuring repeatable filter performance through the use of nanoimprint lithography.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If microfilters are integrated into microfluidic channels using conventional assembly processes, then filter integration is achieved, but the assembly process becomes complex and filter performance becomes inconsistent

Engineering Contradiction:
Improvefilter performance consistencyVSAvoidassembly process complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent merges the filter structure directly into the microchannel substrate using embossing technology, eliminating the need for separate filter components and complex assembly processes. The filter and channel are formed as an integrated single structure, resolving the contradiction between integration and assembly complexity

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The embossing process creates a precise copy of the filter pattern from a mold directly into the substrate material. This copying mechanism ensures consistent filter characteristics across multiple devices while simplifying the manufacturing process to a single-step formation rather than multi-component assembly

Inventive Principle:
Principle #26Copying

2Device complexity

If filters are formed into substrate by embossing, then assembly complexity is reduced, but control over filter characteristics such as particle filtration size becomes limited

Engineering Contradiction:
Improveassembly process simplicityVSAvoidfilter characteristic control
Core Design Contradiction:
Device complexityVSManufacturing precision

Solution Approach 1:

The embossing mold can be designed with varying local features to create different filter pore sizes, densities, and patterns in different regions of the microchannel. This allows precise control over filter characteristics while maintaining the simplicity of the embossing formation process

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

By changing the parameters of the embossing process (such as embossing depth, pressure, temperature, and mold design), the filter characteristics including pore size and density can be precisely controlled. This enables tailored filter performance for different applications while using the same simple embossing formation method

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This method enables reliable and repeatable fabrication of microfluidic channel filters with consistent parameters, simplifying sample preparation and improving the accuracy of downstream analysis by ensuring precise filtration.

Implementation Method 1

photo-polymerizing the emulsion at the predefined location to form the filter

Methodology Applied
Scientific EffectPhoto-polymerization: Photopolymerisation

Implementation Method 2

curing the deposited material, thereby forming the microfluidic channel filter

Methodology Applied
Scientific EffectThermal curing:

Data Source

PatentEP3368218B1Microfluidic channel filter
Publication Date: 2020.04.01 HEWLETT PACKARD DEVELOPMENT COMPANY LP
  • EP3368218B1 patent drawingFigure 1~5
  • EP3368218B1 patent drawingFigure 6~7
  • EP3368218B1 patent drawingFigure 8

AI summary

In an example implementation, a method of fabricating a microfluidic channel filter, includes depositing an imprintable material in a microfluidic channel, pressing an imprint stamp with a filter pattern into the imprintable material, curing the imprintable material, and removing the imprint stamp from the imprintable material.