Microfluidic Foil Structure for Precision Fluid Metering

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Solution Overview

Problem

The production of microfluidic structures with precise three-dimensional contours is cost-intensive and requires expensive phototechnical methods, making it challenging to create structures with dimensions below one micron, and existing methods are laborious and expensive for fluid network structuring.

Innovation Solution

A method involving a flat foil or film applied to a flat substrate, sealed by lamination with a heated die having recesses, allowing the material to flow and form wedges or beads, creating microfluidic structures without pre-structuring substrates or membranes, enabling a single-step production of fluid valves with improved fluid-conveying properties.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If phototechnical methods are used to create precise three-dimensional contours, then manufacturing precision is improved, but device complexity and production cost increase

Engineering Contradiction:
Improveprecision of three-dimensional contoursVSAvoidcomplexity of phototechnical methods
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent replaces complex phototechnical methods with a simple thermal lamination process. A heated die with recesses is pressed against the foil substrate, using thermal and mechanical energy to directly form the three-dimensional contours. This mechanical-thermal approach substitutes the need for expensive photolithography equipment and processes, achieving the same manufacturing precision through a simpler system.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The invention changes the physical parameters of the material during processing by heating the foil above its glass transition temperature, making it pliable and capable of flowing into the recesses of the die. This parameter change allows the material to be shaped at relatively low pressures and temperatures compared to traditional methods, simplifying the manufacturing process while maintaining high precision contours.

Inventive Principle:
Principle #35Parameter changes

2Manufacturing precision

If phototechnical methods are used to create structures with dimensions below one micron, then manufacturing precision is improved, but production cost increases

Engineering Contradiction:
Improvedimensions below one micronVSAvoidproduction cost
Core Design Contradiction:
Manufacturing precisionVSEase of manufacture

Solution Approach 1:

The patent replaces expensive phototechnical methods with a thermal lamination process using a heated die. The die, containing the negative of the desired microstructure, is pressed against the heated foil, causing the material to flow and replicate the fine contours. This mechanical replication method achieves sub-micron precision without requiring expensive photolithography equipment, masks, and cleanroom facilities.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The invention utilizes the glass transition of the polymer foil material. By heating the foil above its glass transition temperature, the material transitions from a rigid state to a pliable state, allowing it to flow and conform to the fine features of the die recesses. This phase transition enables the formation of sub-micron structures through a simple thermal-mechanical process rather than expensive phototechnical methods.

Inventive Principle:
Principle #36Phase transitions

3Manufacturing precision

If multiple steps are used for fluid network structuring, then manufacturing precision is improved, but productivity decreases

Engineering Contradiction:
Improvefluid network structuring accuracyVSAvoidproduction efficiency
Core Design Contradiction:
Manufacturing precisionVSProductivity

Solution Approach 1:

The patent merges multiple manufacturing steps into a single lamination operation. The heated die with integrated recesses simultaneously forms all the fluid network channels, chambers, and connections in one pressing action. This eliminates the need for sequential steps such as separate channel formation, chamber creation, and connection establishment, thereby maintaining manufacturing precision while dramatically improving productivity.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The die is pre-formed with the complete negative of the desired fluid network structure, including all channels, chambers, and interconnections. This preliminary preparation of the tool allows all features to be created in a single lamination step, eliminating the need for multiple sequential manufacturing operations and significantly enhancing production efficiency.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This method simplifies the production of microfluidic structures, reduces costs, and enables the creation of structures with nanometer or micron-scale dimensions, providing enhanced fluid-conveying properties and allowing for the production of small-capacity chambers and efficient liquid metering systems.

Implementation Method 1

the material of which the foil (2) and/or substrate (1) consist softens and flows

Methodology Applied
Scientific EffectThermal softening: Melting

Implementation Method 2

When the foil (2) and substrate (1) are heated above the glass transition temperature of the foil material

Methodology Applied
Scientific EffectThermal expansion: Thermal Expansion

Implementation Method 3

A first polymer film is placed on a substrate and attached to this substrate, in particular by lamination

Methodology Applied
Scientific EffectLamination: Lamination

Implementation Method 4

The foil is joined together in parts by the effect of pressure and heat

Methodology Applied
Scientific EffectHeat bonding: Welding

Implementation Method 5

those microfluidic structures and devices that make use of the capillary effect or pressure differences to convey a liquid

Methodology Applied
Scientific EffectCapillary action: Capillary Action

Implementation Method 6

those microfluidic structures and devices that make use of the capillary effect or pressure differences to convey a liquid

Methodology Applied
Scientific EffectPressure gradient: Pressure Gradient

Data Source

PatentUS8580209B2Microfluidic foil structure for metering of fluids
Publication Date: 2013.11.12 BOEHRINGER INGELHEIM MICROPARTS GMBH
  • US8580209B2 patent drawing
  • US8580209B2 patent drawing
  • US8580209B2 patent drawing

AI summary

A microfluidic device meters liquids into a network of channels or chambers partly formed by a film partly attached to and above a substrate, the network permitting flow of fluid above the substrate. To form a channel or chamber, the edge zone between unattached and attached portions of the film forms a wedge of material by viscous flow of film material as the film is laminated to the substrate, this wedge forming a transition between the chamber wall and the substrate, raising the wall above the plane of the substrate. Film is laminated with a mask having an opening, the mask pressed onto the film under pressure and/or with heat. The film is brought to a temperature to produce a viscous flow of film and/or substrate medium into the region of the opening, forming a wedge of material as the film bulges up at the opening to form a chamber.