Microfluidic Dispenser Induction Heating for Inhalable Substance Dosing

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Solution Overview

Problem

Existing inhalable substance dispenser devices face limitations such as direct contact between electrodes and fluids leading to contamination, excessive heating causing substance degradation or harmful reactions, and low precision in dose control.

Innovation Solution

A microfluidic dispenser device with a nebulizer system where a heater, separated from the liquid, rapidly heats a thin layer to generate vapor bubbles, allowing precise control over the delivery of inhalable substances without overheating the entire fluid volume, using semiconductor manufacturing techniques for accurate dosing and contamination prevention.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Temperature

If a resistive electrode is placed in direct contact with the fluid to enable heating and delivery, then the heating function is achieved, but contamination and release of harmful substances occur

Engineering Contradiction:
Improveheating capabilityVSAvoidcontamination and harmful substance release
Core Design Contradiction:
TemperatureVSObject-affected harmful factors

Solution Approach 1:

The heating system is segmented into separate functional zones: an induction heating zone that heats the chamber walls and a separate vaporization zone where liquid is delivered. This segmentation allows heating without direct electrode-contact contamination, as the induction field heats structures that then transfer heat to the liquid indirectly.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The chamber walls and intermediate structures act as thermal mediators between the induction heating field and the liquid. The induction coil heats the chamber walls, which then conduct heat to the liquid, eliminating the need for direct electrode-liquid contact and preventing contamination.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Productivity

If the entire volume of fluid in the chamber is heated to boiling point for delivery, then sufficient vapor generation is achieved, but thermal degradation and harmful reactions of substances occur

Engineering Contradiction:
Improvevapor generation rateVSAvoidthermal degradation and harmful reactions
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

Heating is applied locally rather than uniformly to the entire fluid volume. The induction heating targets specific chamber regions and the vaporization occurs at controlled locations near the nozzle, allowing sufficient vapor generation while avoiding widespread thermal degradation of the substance.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

Only the necessary portion of the liquid is heated to vaporization temperature at the point of delivery, rather than heating the entire chamber volume. This partial action achieves the required productivity for vapor generation while minimizing the total thermal energy input and preventing excessive heating effects.

Inventive Principle:
Principle #16Partial or excessive action

3Ease of operation

If traditional resistive heating is used to deliver inhalable substances, then the delivery function is achieved, but precision in controlling the doses delivered is reduced

Engineering Contradiction:
Improvedelivery functionVSAvoiddose control precision
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The system incorporates feedback mechanisms including flowmeters that detect flow rate, temperature sensors that monitor heating levels, and control circuits that adjust power delivery based on detected parameters. This feedback enables precise control of the dose delivered by adjusting heating duration and intensity based on real-time measurements.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

Traditional mechanical dose-control mechanisms are replaced with electronic control systems that use electromagnetic induction for heating and electronic sensors for measurement. This substitution enables more precise and programmable dose control through electronic regulation of heating parameters rather than mechanical adjustments.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables precise and controlled delivery of inhalable substances with reduced risk of contamination and thermal degradation, achieving accurate dosing and uniform cloud formation for effective inhalation.

Implementation Method 1

an induction coil, arranged at a distance from the liquid, is supplied by a driving device with pulsating electric current so as to generate, in the liquid, vapor bubbles capable of expelling a corresponding volume of liquid to be delivered through the nozzle

Methodology Applied
Scientific EffectElectromagnetic induction: Electromagnetic Induction

Implementation Method 2

The coil traversed by current remains relatively cold, but generates a magnetic field that heats the spongy body and the liquid until it causes expulsion of the latter

Methodology Applied
Scientific EffectInduction heating: Induction Heating

Implementation Method 3

vapor bubbles capable of expelling a corresponding volume of liquid to be delivered through the nozzle

Methodology Applied
Scientific EffectAcoustic cavitation: Acoustic Cavitation

Data Source

PatentUS12251508B2Microfluidic dispenser device for delivering inhalable substances
Publication Date: 2025.03.18 STMICROELECTRONICS SRL
  • US12251508B2 patent drawing
  • US12251508B2 patent drawing
  • US12251508B2 patent drawing

AI summary

A microfluidic dispenser device of inhalable substances includes a casing, housed in which are a driving circuit and a microfluidic cartridge having a tank that contains a liquid to be delivered. The microfluidic cartridge is provided with at least one nebulizer controlled by the driving device. The nebulizer includes: a substrate; a plurality of chambers formed on the substrate and fluidically coupled to the tank for receiving the liquid to be delivered; and a plurality of heaters, which are formed on the substrate in positions corresponding to respective chambers, are thermally coupled to the respective chambers and are separated from the respective chambers by an insulating layer, and are controlled by the driving device. Each chamber is fluidically connected with the outside by at least one respective nozzle.