Microfluidic Channel Membrane Formation Through Pervaporation

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Solution Overview

Problem

Existing methods for manufacturing polymer membranes are complicated, difficult to adjust porosity, and limited in producing heterogeneous membranes in parallel.

Innovation Solution

A method and apparatus using pervaporation-induced flow to assemble particles inside a microfluidic channel, forming membranes with nanopores by flowing fluids through interconnected channels with a gas permeable member, allowing control over particle size and type for diverse membrane configurations.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If conventional methods are used to manufacture polymer membranes, then membranes can be produced, but the manufacturing process is complicated and difficult to adjust porosity

Engineering Contradiction:
Improveporosity controlVSAvoidmanufacturing process complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The manufacturing process is segmented into distinct functional zones within the microfluidic device: a first microchannel for particle suspension introduction, a second microchannel for gas flow, a bridge channel for membrane formation, and a control channel for vapor removal. This segmentation allows independent control of each parameter (particle concentration, gas flow rate, vapor removal) to precisely adjust porosity while simplifying the overall process through modular design

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Porosity is adjusted by changing physical parameters during the manufacturing process: particle concentration in the suspension, gas flow rate through the second microchannel, and vapor removal rate through the control channel. By controlling these parameters, the desired porosity can be achieved without complex post-processing or multiple manufacturing steps

Inventive Principle:
Principle #35Parameter changes

2Adaptability or versatility

If conventional methods are used to manufacture polymer membranes, then membranes can be produced, but there is a limitation in manufacturing heterogeneous membrane serially arranged

Engineering Contradiction:
Improveheterogeneous membrane production capabilityVSAvoidprocess complexity for parallel production
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The microfluidic device is designed with universal components that can handle different particle types and configurations. The first microchannel can introduce various particle suspensions, the second microchannel can supply different gas flows, and the bridge channel can form different membrane types. This multi-functionality allows serial production of heterogeneous membranes without requiring separate manufacturing processes for each membrane type

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The invention transitions from conventional planar membrane manufacturing to a three-dimensional microfluidic approach with vertically stacked channels. The first microchannel, second microchannel, bridge channel, and control channel are arranged in different spatial dimensions, enabling complex membrane structures and heterogeneous arrangements to be formed simultaneously in a single device

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

3Productivity

If conventional methods are used to manufacture polymer membranes, then membranes can be produced, but a complicated process is required to manufacture a plurality of membranes in parallel

Engineering Contradiction:
Improveparallel membrane production capacityVSAvoidprocess complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

Multiple membrane formation processes are merged into a single integrated microfluidic device. The first microchannel, second microchannel, bridge channel, and control channel work simultaneously to form multiple membranes in parallel within the same device structure. This merging eliminates the need for separate manufacturing processes for each membrane, achieving high productivity without proportionally increasing process complexity

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables easy formation of membranes with controlled pore sizes and materials, facilitating the production of homogeneous or heterogeneous arrays with adjustable properties.

Implementation Method 1

a first fluid in the bridge channel is pervaporated to the control channel by flow of the control gas through the gas permeable member

Methodology Applied
Scientific EffectPervaporation: Pervaporation

Data Source

PatentUS12420278B2Method of manufacturing microfluidic channel with membrane formed therein and apparatus for forming membrane inside the microfluidic channel
Publication Date: 2025.09.23 UNIST (ULSAN NAT INST OF SCI & TECH)
  • US12420278B2 patent drawing
  • US12420278B2 patent drawing
  • US12420278B2 patent drawing

AI summary

Provided is a method of manufacturing a microfluidic channel with a membrane formed therein, the method including: preparing an apparatus for forming a membrane, the apparatus for forming the membrane including a first microfluidic channel, a second microfluidic channel being spaced apart from the first microfluidic channel, a bridge channel having a microchannel structure for communicating the first microfluidic channel and the second microfluidic channel with each other, and a control channel, which is partitioned by a gas permeable member from the bridge channel and through which gas flows; a fluid flowing operation in which a first fluid in a liquid state for moving first microparticles flows in the first microfluidic channel and a control gas in a gaseous state flows in the control channel; and forming a membrane having nanopores.