Microfluidic Device With Elastic Membrane For Pressure Control

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Solution Overview

Problem

Microfluidic devices require precise pressure control for reliable operation, but existing systems often rely on complex and costly external pressure generators, which can be unstable and increase manufacturing and maintenance costs.

Innovation Solution

A microfluidic device design that uses a membrane with a predetermined displacement volume, allowing it to maintain constant pressure within the cavity by expanding and reducing volume, independent of external pressure fluctuations, enabling reliable and cost-effective pressure control without the need for complex external generators.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If external pressure generators are used to control pressure in microfluidic devices, then pressure control is achieved, but device complexity and cost increase

Engineering Contradiction:
Improvepressure control reliabilityVSAvoidexternal pressure generator complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The invention extracts the pressure control function from external pressure generators and relocates it into the microfluidic device itself through elastic membranes with predetermined displacement volumes. This eliminates the need for complex external pressure generation equipment while maintaining reliable pressure control within the device.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The microfluidic device performs its own pressure control function through integrated elastic membranes that automatically regulate pressure based on their predetermined displacement volumes. The device serves itself by using internal elastic elements to generate and maintain required pressure levels without external assistance.

Inventive Principle:
Principle #25Self-service

2Stress or pressure

If external pressure generators are used, then pressure can be supplied, but manufacturing and maintenance costs increase

Engineering Contradiction:
Improvepressure supply capabilityVSAvoidmanufacturing cost
Core Design Contradiction:
Stress or pressureVSEase of manufacture

Solution Approach 1:

The invention replaces expensive external pressure generators with inexpensive elastic membranes that are integrated directly into the microfluidic device. These membranes are simple, disposable components that eliminate the need for costly external pressure generation equipment, significantly reducing manufacturing and maintenance costs.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

3Stress or pressure

If external pressure generators are used, then pressure control is possible, but stability decreases due to external fluctuations

Engineering Contradiction:
Improvepressure controlVSAvoidpressure stability
Core Design Contradiction:
Stress or pressureVSStability of the object's composition

Solution Approach 1:

The elastic membranes with predetermined displacement volumes act as feedback mechanisms that automatically adjust to maintain stable pressure. When external pressure fluctuates, the membranes expand or contract to compensate, ensuring that the pressure within the microfluidic device remains stable and不受 external variations.

Inventive Principle:
Principle #23Feedback

4Adaptability or versatility

If multiple pressure levels are required, then microfluidic functions can be performed, but the number of external pressure generators increases

Engineering Contradiction:
Improvemicrofluidic function capabilityVSAvoidnumber of pressure generators
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The invention implements different pressure levels at different locations within the microfluidic device by using multiple elastic membranes with different predetermined displacement volumes. Each membrane is tailored to provide the specific pressure level required for its local function, eliminating the need for multiple external pressure generators.

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This design enhances the reliability and cost-effectiveness of pressure control within the microfluidic system, allows for precise pressure specification, and reduces the number of interfaces and potential errors, while enabling both low and high pressure operations.

Implementation Method 1

an elastic membrane (2) arranged between the two polymer layers (1, 3) such that, depending on the pressure applied to the channel (4a), the elastic membrane (2) expands substantially completely into the displacement volume (7a, 7b)

Methodology Applied
Scientific EffectElasticity: Elasticity

Implementation Method 2

the membrane does expand and thus change the pressure in the cavity, but not beyond a predetermined value. The expansion of the membrane reduces the total volume of the cavity, thereby increasing the pressure in the cavity

Methodology Applied
Scientific EffectBoyle's Law: Boyle's Law

Data Source

PatentEP2731721B1Microfluidic device and method for producing a microfluidic device
Publication Date: 2020.04.08 ROBERT BOSCH GMBH
  • EP2731721B1 patent drawingFigure 1a~1b
  • EP2731721B1 patent drawingFigure 2a~2b
  • EP2731721B1 patent drawingFigure 3

AI summary

The invention relates to a microfluidic device comprising at least two layers arranged one above the other, a membrane which is arranged between the two layers, a cavity in one of the two layers, and a channel in the other of the two layers. The membrane is arranged so as to be expandable between the cavity and the channel, said membrane being expandable into at least one specified displacement volume. The invention likewise relates to a method for producing a microfluidic device, to a use of a microfluidic device, and to a microfluidic system.