Asymmetric Microfluidic Membrane Pump for Reliable Port Sealing

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Solution Overview

Problem

Existing microfluidic diaphragm pumps have multiple moving parts, complex fabrication, and are prone to valve malfunction, leading to decreased efficiency.

Innovation Solution

A microfluidic pump design with a single flexible drive membrane that acts as a valve, featuring asymmetric pumping chamber and port dimensions, allowing for simplified fabrication and enhanced efficiency by sealing and unsealing fluidic ports through pressure differentials.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If multiple moving parts (drive diaphragm, inlet non-return valve, outlet non-return valve) are used in known diaphragm pumps, then the pump can achieve fluid pumping function, but the device complexity increases and reliability decreases due to more components that can malfunction

Engineering Contradiction:
Improvevalve malfunction likelihoodVSAvoidnumber of moving parts
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent combines the drive diaphragm and the outlet non-return valve into a single integrated component. The drive diaphragm itself forms the valve mechanism through its interaction with the pumping chamber geometry, eliminating the need for a separate outlet non-return valve. This merging reduces the number of moving parts from three to two, thereby improving reliability and reducing complexity.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The drive diaphragm serves dual functions: it acts as both the pumping element (moving fluid by changing chamber volume) and as the outlet valve (preventing backflow through its interaction with the chamber geometry). This multi-functionality eliminates the need for separate components, reducing device complexity while maintaining pumping functionality.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Reliability

If check valves are used as non-return valves in diaphragm pumps, then the pump can prevent backflow, but the fabrication complexity increases and valve malfunction risk increases

Engineering Contradiction:
Improvebackflow prevention reliabilityVSAvoidfabrication complexity
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The outlet non-return valve function is merged with the drive diaphragm structure. The diaphragm's interaction with the pumping chamber geometry creates the valve action, eliminating the need for a separate check valve component. This integration simplifies fabrication by reducing the number of parts that need to be manufactured and assembled.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent extracts the valve function from a separate check valve component and integrates it directly into the drive diaphragm structure. This eliminates the need for separate valve fabrication and assembly, reducing manufacturing complexity while maintaining backflow prevention capability.

Inventive Principle:
Principle #2Taking out (Extraction)

3Ease of manufacture

If a symmetric pumping chamber design is used, then the fabrication is simpler, but the sealing efficiency of fluidic ports decreases

Engineering Contradiction:
Improvefabrication simplicityVSAvoidport sealing efficiency
Core Design Contradiction:
Ease of manufactureVSReliability

Solution Approach 1:

The patent employs an asymmetric pumping chamber design where the chamber geometry is specifically configured to work with the drive diaphragm for effective port sealing. The asymmetric shape allows the diaphragm to seal both inlet and outlet ports effectively during its cycling motion, improving sealing efficiency while the overall design remains manufacturable through standard microfabrication techniques.

Inventive Principle:
Principle #4Asymmetry

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The design reduces the likelihood of valve malfunction and simplifies fabrication, while increasing pump efficiency by using a single moving part that functions as both a diaphragm and valve, ensuring reliable fluid control.

Implementation Method 1

The asymmetric design facilitates the sealing and unsealing of the fluidic ports by the pressure differential in the pressure chamber

Methodology Applied
Scientific EffectPressure differential: Pressure Gradient

Implementation Method 2

A flexible drive membrane intersects the pumping chamber such that a pressure chamber is created on the side of the drive membrane which is open to the control port

Methodology Applied
Scientific EffectElastic deformation: Elasticity

Data Source

PatentUS12601342B2Fluid-actuated microfluidic membrane pump with differently-sized inlet and outlet ports
Publication Date: 2026.04.14 ALINE INC
  • US12601342B2 patent drawing
  • US12601342B2 patent drawing
  • US12601342B2 patent drawing

AI summary

A microfluidic pump with a movable drive membrane (diaphragm), a pumping chamber, at least two fluidic ports on one side of the diaphragm, and at least one control port on an opposing side of the diaphragm is provided. A flexible drive membrane intersects the pumping chamber such that a pressure chamber is created on the side of the drive membrane which is open to the control port, and a fluid flow chamber is created on the side of the drive membrane which is open to the fluidic ports. The drive membrane acts as a valve sealing and unsealing the fluidic ports and fluid flow through the flow chamber. The microfluidic pump has an asymmetric design which facilitates the sealing and unsealing of the fluidic ports by the pressure differential in the pressure chamber.