Monocrystalline Microfluidic Nozzle Alignment for Consistent Aerosols

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Solution Overview

Problem

Existing microfluidic device manufacturing methods, particularly for nozzles used in inhalation devices, suffer from inaccuracies due to cutting or sawing processes, leading to misalignments and increased reject rates, which affect the quality of the aerosol produced.

Innovation Solution

The method involves using mono-crystalline materials and aligning microfluidic structures with the crystal orientation line or plane during fabrication, followed by cleaving along these lines to ensure precise alignment and reduce misalignments.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If cutting or sawing processes are used to separate nozzles from the wafer, then batch fabrication of multiple nozzles is achieved, but misalignment and precision errors occur in the channel exits

Engineering Contradiction:
Improvebatch fabrication of multiple nozzlesVSAvoidalignment of channel exits
Core Design Contradiction:
ProductivityVSManufacturing precision

Solution Approach 1:

The patent applies preliminary action by pre-aligning the channel exits with the crystal orientation lines of the mono-crystalline wafer before the cutting process. This ensures that when the wafer is later sawed or cleaved, the channel exits remain precisely aligned along the crystal orientation, compensating for any cutting variations and maintaining manufacturing precision while enabling batch fabrication.

Inventive Principle:
Principle #10Preliminary action

2Adaptability or versatility

If traditional multi-step fabrication processes are used, then flexibility in material selection is maintained, but the number of fabrication steps and complexity increase

Engineering Contradiction:
Improvematerial selection flexibilityVSAvoidnumber of fabrication steps
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent merges multiple fabrication steps into a single integrated process by fabricating nozzles directly from mono-crystalline materials using crystal orientation alignment. Instead of separately creating nozzles and then assembling them, the invention combines material selection, structure fabrication, and alignment into one unified approach, reducing overall process complexity while maintaining material versatility.

Inventive Principle:
Principle #5Merging (Combining)

3Ease of manufacture

If conventional nozzle fabrication methods are used, then standard manufacturing procedures are followed, but aerosol quality consistency deteriorates due to alignment variations

Engineering Contradiction:
Improvestandard manufacturing proceduresVSAvoidaerosol quality consistency
Core Design Contradiction:
Ease of manufactureVSReliability

Solution Approach 1:

The patent applies parameter changes by utilizing the crystal orientation parameters of mono-crystalline materials as a reference framework. By aligning channel exits with specific crystal orientation lines and cleaving along these orientations, the invention transforms the manufacturing approach from relying on mechanical alignment tolerances to utilizing inherent crystallographic parameters, thereby improving aerosol quality consistency while maintaining ease of manufacture.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enhances precision and reproducibility, reducing the number of unusable devices and improving the quality and consistency of the aerosol output.

Implementation Method 1

separating said microfluidic device from the substrate by cleaving the wafer along the crystal orientation line or plane

Methodology Applied
Scientific EffectCleavage along crystal orientation: Fracture Mechanics

Data Source

PatentUS20260034315A1Microfluidic devices and methods of producing
Publication Date: 2026.02.05 INVOX BELGIUM NV
  • US20260034315A1 patent drawing
  • US20260034315A1 patent drawing
  • US20260034315A1 patent drawing

AI summary

The invention provides a microfluidic device (1), specifically a nozzle for an inhalation device, comprising at least two microfluidic structures (2A, 2A′), each of said structures (2A, 2A′) is located at a front end (1B) of the microfluidic device; characterized in that the microfluidic device (1) is made at least in part from a mono-crystalline material and wherein said front end (1B) of the microfluidic device (1) and the microfluidic structures (2A, 2A′) are aligned with the crystal orientation line and methods producing said devices and uses thereof.