Microfluidic Peristaltic Pump for Low-Cost Disposable Infusion
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Solution Overview
Problem
Existing microfluidic devices are complex and costly to produce, making them unsuitable for low-cost, disposable infusion and sampling devices.
Innovation Solution
A microfluidic pump and device comprising an annular body, an elastic collar, and a rigid substrate, which forms a channel for fluid flow and is actuated by a rotary actuator and motor to provide low-cost, high-accuracy fluid delivery.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of manufacture
If conventional microfluidic devices are used, then fluid delivery function is achieved, but manufacturing cost is high and device complexity is high
Solution Approach 1:
The pump is divided into three main segments: an annular body housing, an elastic collar, and a rigid substrate. This segmentation allows each component to be manufactured separately using simpler, lower-cost processes and then assembled, reducing overall manufacturing complexity and cost while maintaining functional integrity
Solution Approach 2:
The elastic collar serves as a flexible component that replaces complex rigid microfluidic channel structures. The collar's elasticity enables it to perform the fluid delivery function through simple compression by the rotary actuator, eliminating the need for complex integrated circuits or multi-layer rigid structures, thereby reducing manufacturing cost and device complexity
2Measurement precision
If conventional microfluidic devices are used, then fluid delivery function is achieved, but accuracy at low flow rates is insufficient
Solution Approach 1:
The pump employs a dynamic compression mechanism where a rotary actuator with compression elements (such as rollers or balls) continuously moves along the elastic collar to create peristaltic waves. This dynamic action allows precise control of fluid flow at very low rates by adjusting the rotation speed and compression force, achieving high accuracy even at flow rates as low as 0.1 mL/h or lower
Solution Approach 2:
The invention replaces conventional mechanical micropump mechanisms (such as moving parts, valves, and seals) with a peristaltic action system. The elastic collar's deformation under rotary compression creates a sealed fluid pathway without requiring traditional mechanical sealing components, thereby achieving high precision at low flow rates with simpler mechanics
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The microfluidic pump achieves constant and accurate low-flow rate fluid delivery, reducing manufacturing costs and enhancing the accuracy of fluid administration, even at very low flow rates.
Implementation Method 1
an elastic collar fixedly attached to the bottom surface of the annular body, the elastic collar comprising a flange disposed around the periphery thereof
Implementation Method 2
a rotary actuator and motor configured to compress a portion of the elastic collar of the microfluidic device
Data Source
AI summary
A microfluidic device is provided for managing fluid flow in disposable infusion devices, thereby providing periodic or constant flow of fluid even at very low doses and/or flow rates. Pumps utilizing the microfluidic device, as well as methods for manufacture and performing a microfluidic process are also provided.