Microfluidic Pump Pressure Control for Mobile Peritoneal Dialysis

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Solution Overview

Problem

Conventional peritoneal dialysis systems rely on gravity for fluid management, which can be cumbersome and limit patient mobility, and often involve direct contact with medical fluids, increasing the risk of contamination and wear.

Innovation Solution

A microfluidic pump system using piezoelectric technology generates positive and negative pressures to manage fluid flow without direct contact, incorporating sensors and valves for precise control and monitoring, allowing for flexible placement and reduced contamination risk.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If gravity-based fluid management is used in conventional peritoneal dialysis systems, then the system structure is simple, but patient mobility is limited and fluid management becomes cumbersome

Engineering Contradiction:
Improvepatient mobilityVSAvoidsystem structure
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The patent replaces the gravity-based mechanical fluid management system with a microfluidic pump system that uses controlled pressure differentials (positive and negative pressures) to drive fluid flow. This substitution enables active control of dialysate infusion and effluent drainage, freeing patients from position constraints and improving mobility while maintaining manageable system complexity through integrated control mechanisms.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Reliability

If direct contact with medical fluids is implemented in conventional systems, then fluid management is straightforward, but contamination risk and component wear increase

Engineering Contradiction:
Improvecontamination riskVSAvoidfluid management system
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent introduces an intermediary approach where the microfluidic pump handles air or inert gas rather than directly contacting medical fluids. The pump generates pressure differentials that act through fluid interfaces (bag walls, valve mechanisms) to control dialysate flow and effluent drainage without direct fluid-pump contact. This intermediary mechanism reduces contamination risk and wear while maintaining effective fluid management through pressure-controlled flow regulation.

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system provides efficient, reliable, and hygienic fluid management, enhancing patient mobility and reducing contamination risks while improving the efficiency and cost-effectiveness of peritoneal dialysis treatments.

Implementation Method 1

A microfluidic pump system using piezoelectric technology generates positive and negative pressures to manage fluid flow without direct contact

Methodology Applied
Scientific EffectPiezoelectric effect: Piezoelectric Effect

Data Source

PatentUS20250352710A1Systems for Medical Fluid Pumps and Related Methods
Publication Date: 2025.11.20 FRESENIUS MEDICAL CARE HOLDINGS INC
  • US20250352710A1 patent drawing
  • US20250352710A1 patent drawing
  • US20250352710A1 patent drawing

AI summary

This disclosure relates to systems for medical fluid pumps and related methods. In some implementations, a system includes a system for draining fluid from a peritoneal cavity of a patient comprising a microfluidic pump; a drain bag fluidly coupled to the microfluidic pump; and an inlet line coupled to the drain bag, wherein the microfluidic pump is configured to apply a negative pressure to an interior of the drain bag to draw effluent from a peritoneal cavity of the patient along the inlet line and into the drain bag. In some implementations, a system for performing peritoneal dialysis includes a microfluidic pump; a dual chamber bag fluidly coupled to the microfluidic pump, where the dual chamber bag includes an effluent chamber configured to be fluidly coupled to a peritoneal cavity of a patient; a dialysate chamber; and a flexible membrane separating the effluent chamber from the dialysate chamber.