Microfluidic Pump Thermal Control via Active Feedback

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Solution Overview

Problem

Conventional microfluidic pumps using thermal vapor bubbles for fluid transport face challenges in heat dissipation, leading to undesirable temperature changes that affect fluid composition and pump performance, as passive cooling systems may either fail to dissipate heat adequately or remove too much heat, causing issues with fluid suitability and pump operation.

Innovation Solution

A thermally-controlled microfluidic pump with a pump temperature controller that monitors temperatures and adjusts the activation of resistive heating elements to maintain temperatures within a selected range, using a substrate heater to regulate fluid temperature and enhance heat dissipation through active and passive means.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Loss of energy

If passive cooling systems are designed with higher heat dissipation rates, then heat dissipation capability is improved, but the fluid may be cooled below minimum operating temperature causing poor flowability and clumping

Engineering Contradiction:
Improveheat dissipation rateVSAvoidfluid operating temperature
Core Design Contradiction:
Loss of energyVSTemperature

Solution Approach 1:

The cooling system transitions from a static passive design to a dynamic active system that adjusts cooling power based on real-time temperature feedback. The controller modulates the cooling element operation to match actual heat generation, enabling the system to adapt to varying operational conditions and maintain fluid temperature within the optimal range regardless of cooling capacity.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

A temperature sensing and control system is implemented where temperature sensors continuously monitor the fluid or substrate temperature, and the controller uses this feedback to adjust the cooling element activation. This closed-loop control ensures that cooling is applied only when and where needed, preventing over-cooling while effectively managing heat dissipation under various operational loads.

Inventive Principle:
Principle #23Feedback

2Productivity

If pump heating elements are activated frequently to maintain pumping performance, then fluid transport capability is improved, but fluid temperature rises above maximum operating temperature causing degradation

Engineering Contradiction:
Improvepumping rateVSAvoidfluid temperature
Core Design Contradiction:
ProductivityVSTemperature

Solution Approach 1:

The controller receives continuous temperature feedback from sensors positioned to monitor fluid or substrate temperature. Based on this feedback, the controller dynamically adjusts the activation frequency and duration of pump heating elements, reducing or eliminating heating cycles when temperature approaches maximum limits while maintaining pumping functionality when temperatures are acceptable.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system transitions from fixed pumping cycles to dynamic pumping operation that adapts to thermal conditions. The controller modulates pump heating element activation based on real-time temperature measurements, enabling the system to optimize between maintaining pumping performance and preventing fluid overheating under varying operational demands.

Inventive Principle:
Principle #15Dynamics

3Stability of the object's composition

If active temperature control is implemented to maintain temperatures within operational range, then temperature stability is improved, but device complexity increases due to additional control components

Engineering Contradiction:
Improvetemperature stabilityVSAvoidcontrol system complexity
Core Design Contradiction:
Stability of the object's compositionVSDevice complexity

Solution Approach 1:

The system incorporates temperature sensors and control logic that automatically monitor and adjust heating and cooling operations without external intervention. The controller self-regulates pump heating element and cooling element activation based on temperature feedback, enabling autonomous temperature management that maintains stability while minimizing the need for complex external control systems.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The temperature control functionality is integrated into the existing pump control architecture, combining temperature sensing, processing, and actuation control within a unified controller. This integration approach consolidates multiple control functions into a single system, reducing overall device complexity while maintaining comprehensive temperature management capability.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This solution effectively prevents overheating of the fluid and the pump, ensuring fluid suitability and optimal performance by actively managing heat generation and dissipation, thereby maintaining fluid characteristics and pump efficiency across varying conditions.

Implementation Method 1

The pump heating elements are resistive pump heating elements that are rapidly heated to cause supercritical heating of the fluid leading to formation of thermal vapor bubbles

Methodology Applied
Scientific EffectJoule heating: Joule Heating

Implementation Method 2

thermal vapor bubbles generated using supercritical heating... By sequencing the activation of the pump heating elements, the fluid flow is controlled

Methodology Applied
Scientific EffectThermal expansion: Thermal Expansion

Implementation Method 3

Conventional microfluidic pumps employing thermal vapor bubbles to transport fluids rely on passive cooling to dissipate the heat generated during the creation of the thermal vapor bubbles. The rate of heat dissipation is determined by the volume, surface area, and thermal conductivity of conventional microfluidic pump components (e.g., the substrate)

Methodology Applied
Scientific EffectThermal conduction: Conduction (thermal)

Data Source

PatentEP3400388B1Microfluidic pump with thermal control
Publication Date: 2020.04.08 FUNAI ELECTRIC CO LTD
  • EP3400388B1 patent drawingFigure 1~2
  • EP3400388B1 patent drawingFigure 3A~3C
  • EP3400388B1 patent drawingFigure 4

AI summary

A microfluidic pump with thermal control. The microfluidic pump employs a fluid motivation mechanism that moves microscopic fluid volumes through a conduit using thermal vapor bubbles generated using supercritical heating. Aspects of the microfluidic pump include the use of a pump temperature controller that monitors temperatures associated with the microfluidic pump and slows or pauses operation of the microfluidic pump to reduce the rate at which heat is generated allowing additional time for heat to be passively dissipated. Controlling the upper microfluidic pump temperature prevents or reduces overheating of the fluid being pumped that renders the fluid less suitable or unsuitable for its intended purpose or harm to the microfluidic pump. Other aspects of the pump temperature controller include an optional substrate heater that helps raise the fluid temperature to a selected operational range for better performance of the fluid and/or the microfluidic pump.