Microfluidic Sampling Seal With Elastic Venting for Uniform Mixing

The second channel is segmented by multiple partition columns that divide the channel into multiple sub-channels. This segmentation creates a complex flow path that enhances mixing efficiency by increasing the interaction between sample and reagent streams while maintaining a relatively simple overall structure.

The partition columns are designed with porous characteristics that allow fluid passage while maintaining structural integrity. This porous design enables efficient mixing through diffusion and advection across the partition structures without requiring complex external mixing mechanisms.

The sampling structure is merged with the microfluidic chip by integrating the first main body, second main body, and third main body into a unified structure. This combining approach enables automated sampling and mixing operations while using standard microfluidic manufacturing techniques to manage precision requirements.

The integrated sampling structure serves multiple functions including sample intake, mixing, and controlled discharge within a single integrated assembly. This multi-functionality reduces the number of separate components needed, thereby reducing overall integration precision requirements while maintaining high automation.

The sampling structure utilizes vertical dimension by extending the first channel, second channel, and chamber along the height direction. This three-dimensional configuration allows increased sample capacity in the chamber while maintaining efficient absorption pathways through the vertically oriented channels with partition columns.

The channel system is segmented into multiple regions (first channel for intake, second channel for mixing with partitions, third channel for discharge) that are optimized for different functions. This segmentation allows the chamber to be larger for capacity while the channels maintain efficient flow characteristics for absorption.