Microfluidic Sensor for Cultural Heritage Analyte Detection

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Solution Overview

Problem

Current technologies lack sensors capable of continuously monitoring specific analytes, such as ammonia, chlorides, nitrates, and sulphates, directly on the surface of cultural heritage objects, which are essential for effective conservation and restoration, as existing solutions are either too complex or not designed for in-situ monitoring.

Innovation Solution

A microfluidic sensor system comprising a contact surface with an inlet for fluid entry, a polymer matrix reservoir containing a reactive substance that changes color upon analyte detection, and microfluidic ducts to conduct fluids from the object's surface to the reservoir, allowing for visual or spectrometric detection of analytes, enabling continuous monitoring of multiple degradation factors on small, flexible devices.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Difficulty of detecting and measuring

If colorimetric detection systems are used to detect analytes, then detection capability is achieved, but device complexity and cost increase due to receptacles, pumps, valves and detector modules

Engineering Contradiction:
Improveanalyte detection capabilityVSAvoiddevice structure
Core Design Contradiction:
Difficulty of detecting and measuringVSDevice complexity

Solution Approach 1:

The patent extracts the essential detection function from complex colorimetric systems by removing receptacles, pumps, valves and detector modules. Only the reactive substance and its color change response to analytes are retained, creating a simplified sensor that achieves detection capability without the complexity of fluid handling and electronic detection systems.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent employs a disposable sensor design where the reactive substance is contained in a simple support structure. The sensor is intended for single use or limited use, eliminating the need for complex, expensive, and maintainable detection systems. This approach trades device longevity for simplicity and cost-effectiveness.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

2Difficulty of detecting and measuring

If traditional monitoring devices are used, then analyte detection is possible, but portability and ease of use at the contamination site are reduced

Engineering Contradiction:
Improveanalyte detectionVSAvoidportability and ease of use
Core Design Contradiction:
Difficulty of detecting and measuringVSEase of operation

Solution Approach 1:

The patent extracts the detection function from laboratory-based equipment and creates a portable field device. By removing the need for complex instrumentation and reducing the sensor to its essential reactive components, the system becomes easily transportable and operable at contamination sites without requiring laboratory infrastructure.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The sensor is designed to be self-contained and self-operating. The reactive substance automatically responds to analytes upon contact, eliminating the need for external power sources, control systems, or complex operation procedures. This makes the device extremely easy to use in field conditions.

Inventive Principle:
Principle #25Self-service

3Productivity

If sensors are designed for in-situ monitoring on cultural heritage objects, then real-time detection is achieved, but device size and flexibility are compromised

Engineering Contradiction:
Improvereal-time monitoring capabilityVSAvoidsensor size
Core Design Contradiction:
ProductivityVSVolume of moving object

Solution Approach 1:

The patent extracts the monitoring function from bulky traditional sensors and creates a miniaturized device. By retaining only the essential reactive substance and support structure, the sensor achieves real-time detection capability in a compact form factor suitable for placement on cultural heritage objects with complex geometries.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The sensor employs a flexible support structure that can conform to the surfaces of cultural heritage objects. This thin, adaptable design allows the sensor to be placed on objects with complex geometries while maintaining its real-time detection capability, resolving the conflict between monitoring effectiveness and physical adaptability.

Inventive Principle:
Principle #30Flexible shells and thin films

4Difficulty of detecting and measuring

If complex colorimetric systems are deployed, then analyte detection is achieved, but cost and ease of manufacture increase

Engineering Contradiction:
Improveanalyte detection accuracyVSAvoidmanufacturing complexity and cost
Core Design Contradiction:
Difficulty of detecting and measuringVSEase of manufacture

Solution Approach 1:

The patent extracts the detection essence from complex colorimetric systems by removing expensive components like detector modules and fluid handling systems. The simplified design using only reactive substances on simple supports dramatically reduces manufacturing complexity and cost while preserving analyte detection accuracy through the inherent color change response.

Inventive Principle:
Principle #2Taking out (Extraction)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The microfluidic sensor system allows for autonomous, real-time monitoring of analytes on cultural heritage objects, providing a cost-effective, portable, and easy-to-use solution for detecting degradation factors, even in complex geometries, with the ability to monitor multiple analytes simultaneously and respond quickly to changes in analyte concentrations.

Implementation Method 1

The behaviour of fluids on the microscale may differ from macrofluids in factors such as surface tension, energy dissipation and the fluidic resistance

Methodology Applied
Scientific EffectCapillary action: Capillary Action

Implementation Method 2

a reactive substance which is configured to change colour when it enters into contact with at least one analyte present in the fluids emitted by the surface of the object

Methodology Applied
Scientific EffectColor change reaction: Chemical Bonding

Data Source

PatentUS20220379304A1Microfluidic sensor for the detection of analytes
Publication Date: 2022.12.01 UNIV DEL PAIS VASCO EUSKAL HERRIKO UNIBERTSITATEA
  • US20220379304A1 patent drawing
  • US20220379304A1 patent drawing
  • US20220379304A1 patent drawing

AI summary

A microfluidic sensor for the detection of analytes in objects includes a contact surface that may be attached to a surface of the object, an inlet hole in the contact surface for the entry of fluids emitted by the object, and a first reservoir which stores an ionic fluid in the form of a polymer matrix. The polymer matrix includes a reactive substance which changes colour when it enters into contact with the analytes of the fluids emitted by the object. It further includes at least one first microfluidic duct which connects the inlet hole to the first reservoir. A system for the detection of analytes, a method for the manufacture of the microfluidic sensor and the use of the microfluidic sensor for the detection of analytes in works of art are also related.