Low-Voltage Microfluidic Valve Using Dendritic Filament Flow Blocking

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Solution Overview

Problem

Current microfluidic valve technologies face challenges such as reliance on high-voltage sources, complex fabrication, leakage issues, and contamination risks, particularly in regulating fluid flow in microfluidic channels.

Innovation Solution

A low-voltage microfluidic valve device utilizing a reversible petal effect through the growth and retraction of nano-textured dendritic silver filaments on a solid electrolyte surface, which selectively interrupts fluid flow by modifying the interface topography between the fluid and the channel surface, eliminating the need for cumbersome pneumatic elements and reducing contamination risks.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Device complexity

If electrokinetic microvalves are used to control fluid flow, then the mechanism is simple, but high-voltage sources and switches are required

Engineering Contradiction:
Improvevalve mechanism complexityVSAvoidvoltage requirement
Core Design Contradiction:
Device complexityVSUse of energy by moving object

Solution Approach 1:

The patent changes the electrical parameter from high-voltage (electrokinetic) to low-voltage operation by using a different actuation mechanism. The electroactive polymer membrane can be actuated at low voltages through electrostatic attraction between oppositely charged electrodes, eliminating the need for high-voltage power supplies while maintaining simple valve operation.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent replaces the electrokinetic mechanism (which requires high voltage) with an electrostatic actuation mechanism using an electroactive polymer membrane. This substitution allows the same fluid control function to be achieved with low-voltage electrodes, resolving the contradiction between mechanism simplicity and voltage requirements.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Use of energy by moving object

If PDMS membrane deflection is used to interrupt fluid flow, then high-voltage sources are avoided, but device structure and fabrication become complicated

Engineering Contradiction:
Improvevoltage requirementVSAvoiddevice structure complexity
Core Design Contradiction:
Use of energy by moving objectVSDevice complexity

Solution Approach 1:

The patent merges the valve membrane and the actuation structure into a single integrated component. The electroactive polymer membrane serves both as the flow-control element and as the actuator itself, eliminating the need for separate control channels and complex multi-layer PDMS structures. This integration simplifies device structure while maintaining low-voltage operation.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The electroactive polymer membrane performs multiple functions: it acts as the flow-interrupting element, the actuator, and the structural component. This multi-functionality eliminates the need for separate control channels and complex fabrication processes required by traditional PDMS-based valves, resolving the contradiction between avoiding high-voltage and simplifying device structure.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Ease of manufacture

If lateral-deflection membrane microvalves are used, then fabrication is simplified, but channel leakage occurs

Engineering Contradiction:
Improvefabrication simplicityVSAvoidchannel sealing
Core Design Contradiction:
Ease of manufactureVSReliability

Solution Approach 1:

The patent extracts the sealing function from the membrane deflection mechanism itself and implements it through a separate sealing mechanism. The electroactive polymer membrane provides flow control through vertical deflection, while a distinct sealing structure (such as a gasket or O-ring) ensures channel sealing, thereby maintaining both fabrication simplicity and leakage prevention.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent introduces an intermediary sealing element between the membrane and the channel walls to prevent leakage. This intermediary component (such as a compliant gasket) maintains the simple lateral-deflection fabrication approach while adding the necessary sealing function to prevent channel leakage.

Inventive Principle:
Principle #24Intermediary (Mediator)

4Ease of operation

If phase-change microvalves are used to control fluid flow, then flow regulation is achieved, but actuation speed is slow (1 to 10 minutes)

Engineering Contradiction:
Improveflow control capabilityVSAvoidactuation speed
Core Design Contradiction:
Ease of operationVSSpeed

Solution Approach 1:

The patent replaces the thermal phase-change mechanism (which is inherently slow) with an electrostatic actuation mechanism. The electroactive polymer membrane responds to voltage changes within seconds by undergoing electrostatic attraction and rapid deflection, achieving flow control without the 1-10 minute actuation times required by phase-change processes.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent changes the actuation parameter from thermal (phase-change requiring heating/cooling) to electrical (electrostatic field). This parameter change enables rapid response times because electrostatic forces act immediately when voltage is applied, eliminating the thermal inertia that causes slow actuation in phase-change microvalves.

Inventive Principle:
Principle #35Parameter changes

5Ease of operation

If burst microvalves and bubble microvalves are used for actuation, then innovative control is achieved, but sample contamination occurs

Engineering Contradiction:
Improvecontrol capabilityVSAvoidsample contamination
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The patent extracts the actuation function from the fluid itself (burst or bubble mechanisms that introduce foreign elements) and implements it through external electrostatic fields. The electroactive polymer membrane is actuated by voltage applied to external electrodes, completely separating the control mechanism from the sample fluid and eliminating contamination risks while maintaining precise control capability.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent introduces an intermediary electroactive polymer membrane that transduces electrical signals into mechanical motion without contacting the sample fluid. This intermediary layer allows control capability to be achieved through electrical actuation while preventing direct contact between the actuation mechanism and the sample, thereby eliminating contamination.

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device effectively regulates fluid flow in microfluidic channels using a low DC voltage, providing rapid on/off switching capabilities without contaminating samples, with the nano-textured filaments enhancing the adhesive force to control fluid flow efficiently.

Implementation Method 1

A 6 volt bias is applied to grow or dissolve the filaments of tens to hundreds of nanometers in height, depending on the polarity

Methodology Applied
Scientific EffectElectrochemical deposition: Electrodeposition

Implementation Method 2

a membrane positioned proximate to the fluid and configured to alter shape in response to the growth of the nano-textured dendritic metallic filament

Methodology Applied
Scientific EffectMechanical deformation: Deformation

Implementation Method 3

the nano-textured filaments enhancing the adhesive force to control fluid flow efficiently

Methodology Applied
Scientific EffectAdhesion: Adhesive

Data Source

PatentUS11592016B2Low-voltage microfluidic valve device and system for regulating the flow of fluid
Publication Date: 2023.02.28 THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIV OF ARIZONA
  • US11592016B2 patent drawing
  • US11592016B2 patent drawing
  • US11592016B2 patent drawing

AI summary

A low-voltage microfluidic valve device and system for regulating the flow of fluid. One low-voltage microfluidic valve device for regulating the low of fluid includes a nano-textured dendritic metallic filament configured to grow and retract in response to a voltage. The low-voltage microfluidic valve device also includes a microfluidic channel configured to allow fluid flow, wherein the fluid flow is selectively interrupted by the growth of the nano-textured dendritic metallic filament. The low-voltage microfluidic valve device also includes a membrane positioned proximate to the fluid and configured to alter shape in response to the growth of the nano-textured dendritic metallic filament.