Microfluidics Manifold Integrating Discrete Fluid Components

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Solution Overview

Problem

Conventional fluid handling systems for biomedical instruments are bulky due to discrete components, which hinder the development of compact instrumentation, and microfluidics does not adequately address mechanical components like pressure regulators and pumps, leading to manufacturing complexity and reduced robustness.

Innovation Solution

A fluidics module with a microfluidics manifold that integrates off-the-shelf components such as valves, pumps, and connectors, utilizing a 3D spatial network of microfluidic channels to minimize mass, volume, and power, while allowing for robust and efficient fluid handling.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Weight of stationary object

If conventional discrete components are used for fluid handling, then the system is robust and easy to manufacture, but the mass and volume are large

Engineering Contradiction:
ImprovemassVSAvoidcomponent integration
Core Design Contradiction:
Weight of stationary objectVSDevice complexity

Solution Approach 1:

The patent integrates multiple discrete fluid handling components (valves, pumps, regulators, connectors) into a single microfluidics manifold assembly. This merging reduces the overall mass and volume of the fluid handling system while maintaining the functional capabilities of individual components through careful selection and integration of miniaturized elements.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The microfluidics manifold serves as a universal platform that accommodates multiple different fluid handling functions simultaneously. It integrates pressure regulation, pumping, valve control, and fluid routing capabilities into one multi-functional device, eliminating the need for separate discrete components for each function.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Volume of stationary object

If microfluidics is used to remove tubing requirements, then the volume is reduced, but manufacturing becomes more complex and robustness decreases

Engineering Contradiction:
ImprovevolumeVSAvoidmanufacturing complexity
Core Design Contradiction:
Volume of stationary objectVSEase of manufacture

Solution Approach 1:

The patent segments the fluid handling system into a microfluidics manifold core with integrated channels and separate mounting interfaces for discrete components. This segmentation allows the manifold to provide compact fluid routing while discrete components can be selectively integrated where robustness is needed, balancing manufacturing ease with volume reduction.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The microfluidics manifold applies microfluidic channel technology locally where compact routing is most beneficial, while maintaining conventional discrete component interfaces in areas where robustness and ease of manufacture are priorities. This localized application of microfluidics optimizes volume reduction without compromising overall system manufacturability.

Inventive Principle:
Principle #3Local quality

3Weight of stationary object

If greater level of integration is achieved, then mass and volume are reduced, but manufacturing complexity increases

Engineering Contradiction:
ImprovemassVSAvoidmanufacturing complexity
Core Design Contradiction:
Weight of stationary objectVSEase of manufacture

Solution Approach 1:

The patent merges multiple fluid handling functions into a single manifold assembly with integrated microfluidic channels and component mounting interfaces. This consolidation reduces mass by eliminating separate housings and interconnections while the modular design with standardized interfaces keeps manufacturing complexity manageable.

Inventive Principle:
Principle #5Merging (Combining)

Data Source

PatentUS10279347B2Fluidics module
Publication Date: 2019.05.07 DNA MEDICINE INST
  • US10279347B2 patent drawing
  • US10279347B2 patent drawing
  • US10279347B2 patent drawing

AI summary

An integrated fluidics module that reduces mass and volume so that it can readily fit inside a compact biomedical instrument. A fluidics module that integrates discrete components (e.g., pump, connectors, tubing, regulator, and valves) reduces mass and volume requirements.