Microneedle Array Packaging With Deformed Container Support
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Solution Overview
Problem
Microneedle arrays are prone to damage when accommodated in containers due to applied forces, which can compromise their functionality and effectiveness in drug delivery.
Innovation Solution
A method of producing a microneedle array unit involves preparing a microneedle array with a sheet and needles, a container with an accommodating portion and a deformable portion, and deforming the container's outer surface to form protrusions that reduce the opening area, thereby stabilizing the array and preventing damage during accommodation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If force is applied to attach the microneedle array to the applicator by fitting, then the microneedle array can be accommodated in the container, but the microneedle array may be damaged
Solution Approach 1:
The patent applies preliminary action by forming protrusions on the inner wall of the accommodating portion before inserting the microneedle array. These protrusions are pre-formed to guide and support the microneedle array during insertion, preventing damage without requiring forceful attachment. The support members are positioned in advance to receive and stabilize the microneedle array as it is inserted into the container.
2Reliability
If the microneedle array is accommodated in the container, then protection until skin puncture is achieved, but damage may occur during accommodation
Solution Approach 1:
The patent introduces support members as intermediary elements between the microneedle array and the container wall. These support members (protrusions) act as mediators that provide mechanical support and distribution of forces during accommodation, preventing direct contact between the fragile microneedles and the container walls, thus protecting the microneedle array while enabling stable accommodation.
3Ease of operation
If force is applied to fit the microneedle array into the container, then accommodation is achieved, but the functionality and effectiveness may be compromised
Solution Approach 1:
The patent applies local quality by providing support members at specific locations on the inner wall of the accommodating portion rather than uniform reinforcement throughout. The protrusions are strategically positioned to provide localized support where the microneedle array makes contact during insertion, enabling easy accommodation through gravity and minimal force while preserving the delicate structure and functionality of the microneedles.
Data Source
AI summary
Provided is a method of producing a microneedle array unit which is capable of suppressing damage to a microneedle array. The method of producing a microneedle array unit, including an array preparing step of preparing a microneedle array which includes a sheet and a plurality of needles arranged on one surface of the sheet; a container preparing step of preparing a container which includes an accommodating portion defining an opening and a space for accommodating the microneedle array, and a deformable portion disposed on a side opposite to the opening and integrated with the accommodating portion; an accommodating step of accommodating the microneedle array in the accommodating portion of the container by allowing the other surface of the sheet of the microneedle array and the deformable portion of the container to oppose each other; and a deforming step of deforming an outer surface of the accommodating portion inward, which is positioned between the one surface of the sheet of the microneedle array and the opening of the accommodating portion, to form a protrusion that reduces an area of the opening.