Microneedle Glucose Patch With Optical Error Correction
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Solution Overview
Problem
Conventional blood glucose level measurement devices cause pain and discomfort due to the collection of body fluid, and inaccuracies arise from poor adhesion of the patch to the light source control module, leading to errors in glucose level measurement.
Innovation Solution
A blood glucose level measurement apparatus and method utilizing a patch with microneedles to extract body fluid, featuring a photodetector and light sources to measure reflected light from areas with and without microneedles, and a binding structure with uneven surfaces to enhance adhesion and precision.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Object-affected harmful factors
If a patch with microneedles is used to extract body fluid, then pain and discomfort are minimized, but adhesion between the patch and light source control module is poor leading to measurement errors
Solution Approach 1:
The patch surface is divided into two distinct areas: a first area with microneedles for body fluid extraction and a second area without microneedles for light reflection measurement. This segmentation allows the device to simultaneously achieve painless measurement (through microneedle extraction) and accurate measurement (through light reflection from the smooth second area), resolving the contradiction between minimizing pain and ensuring measurement precision.
Solution Approach 2:
The second area of the patch acts as an intermediary element between the light source control module and the body fluid extraction function. By providing a smooth, light-reflective surface in this area, it enables accurate optical measurement while the microneedle area handles fluid extraction, thus mediating between the requirements for adhesion and measurement precision.
2Measurement precision
If conventional collection method is used to measure blood glucose level, then measurement can be performed, but pain and fear are caused to users
Solution Approach 1:
The patent replaces the conventional mechanical puncture method (using needles to draw blood) with a dual-area patch system that combines minimal-invasive microneedle extraction with optical measurement. The second area without microneedles allows light reflection measurement to occur without additional mechanical intrusion, thus maintaining measurement capability while significantly reducing pain and fear associated with conventional blood collection methods.
3Measurement precision
If light reflected from the patch is measured to calculate blood glucose level, then measurement is performed, but adhesion between patch and apparatus is poor causing errors
Solution Approach 1:
The patch is designed with different local qualities in different areas: the first area has microneedles optimized for body fluid extraction, while the second area has a smooth, light-reflective surface optimized for optical measurement. This local differentiation ensures that the light reflection measurement occurs from a stable, well-adhered surface, improving both measurement precision and reliability by ensuring consistent contact between the patch and the light source control module.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The apparatus provides high precision, efficiency, and convenience in measuring blood glucose levels by minimizing pain, reducing errors, and accounting for environmental factors through corrected calculations.
Implementation Method 1
light sources configured to emit light toward the other surface of the patch, a photodetector configured to receive the light received by the enzyme which reacts with the body fluid
Implementation Method 2
including at least one enzyme configured to react with a body fluid of a user so as to measure a blood glucose level in the extracted body fluid
Implementation Method 3
The enzyme may react with glycation products in the body fluid and may generate advanced glycation endproducts (AGEs)
Data Source
AI summary
Disclosed are an apparatus and a method for measuring a blood glucose level. In the blood glucose level measurement apparatus and method, the apparatus coupled to a patch with a microneedle formed in at least one area and configured to calculate a blood glucose level of a body fluid extracted from a user may calculate the blood glucose level by analyzing a reflected light beam reflected from the patch with a microneedle formed in a second area and correct the calculated blood glucose level of the user by analyzing data obtained by measuring a reflected light beam from a first area from which the body fluid is not extracted so as to measure a precise blood glucose level with an error being reduced in consideration of environmental factors influencing measurement.